Concepedia

Mitotic Exit Checkpoint

The Mitotic Exit Checkpoint is a regulatory mechanism in the cell cycle that ensures the faithful segregation of chromosomes before the irreversible transition from mitosis to G1 phase by coupling the completion of anaphase events with the inactivation of cyclin-dependent kinase 1.

52

Publications

5.8K

Citations

243

Authors

116

Institutions

Publications per year

2017–2026

4

Parents

Publications

52

Exit from Mitosis Is Triggered by Tem1-Dependent Release of the Protein Phosphatase Cdc14 from Nucleolar RENT Complex

Wenying Shou, Jae Hong Seol, Christopher Baskerville et al. · Cell · 1999 · 719 citations · Full text

, , +17

Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells

Catherine Lindon, Jonathon Pines · The Journal of Cell Biology · 2004 · 351 citations · Full text

, , +15

Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells

Michael H. A. Schmitz, Michael Held, Veerle Janssens et al. · Nature Cell Biology · 2010 · 337 citations

, , +8

Evidence that Mitotic Exit Is a Better Cancer Therapeutic Target Than Spindle Assembly

Hsiao-Chun Huang, Jue Shi, James D. Orth et al. · Cancer Cell · 2009 · 287 citations · Full text

, , +12

Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C

Katharine L. Sackton, Nevena Dimova, Xing Zeng et al. · Nature · 2014 · 263 citations

, , +14

1–5 of 52

Authors

243

  1. GP
    Gislene Pereira

    Heidelberg University, Germany

    3 publications · 208 citations

    3

    h-index

  2. GL
    Giovanna Lucchini

    University of Milano-Bicocca, Italy

    2 publications · 80 citations

    2

    h-index

  3. SP
    Simonetta Piatti

    University of Milano-Bicocca, Italy

    2 publications · 80 citations

    2

    h-index

  4. KL
    Katharine L. Sackton

    Cornell University, United States

    2 publications · 298 citations

    2

    h-index

  5. FU
    Frank Uhlmann

    The Francis Crick Institute, United Kingdom

    2 publications · 218 citations

    2

    h-index

1–5 of 243

Institutions

116

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    10 publications

    827 citations

  2. Harvard University

    Cambridge, United States

    4 h-index

    20 publications

    4.7K citations

  3. Heidelberg University

    Heidelberg, Germany

    3 h-index

    9 publications

    456 citations

  4. Institute of Molecular Biotechnology

    Vienna, Austria

    2 h-index

    4 publications

    900 citations

  5. Baylor College of Medicine

    Houston, United States

    2 h-index

    8 publications

    1K citations

  6. California Institute of Technology

    Pasadena, United States

    2 h-index

    7 publications

    3.7K citations

  7. The University of Texas Southwestern Medical Center

    Dallas, United States

    2 h-index

    10 publications

    1.2K citations

  8. University of Milano-Bicocca

    Milan, Italy

    2 h-index

    5 publications

    221 citations

1–8 of 116

Venues

  1. The Journal of Cell Biology

    JCB · 7 publications · 799 citations

    7

    h-index

  2. Nature

    4 publications · 796 citations

    4

    h-index

  3. Cell Cycle

    4 publications · 173 citations

    4

    h-index

  4. Current Biology

    4 publications · 407 citations

    4

    h-index

  5. Molecular Biology of the Cell

    MBC · 4 publications · 130 citations

    4

    h-index

1–5