James D. Orth

Regulated Interactions between Dynamin and the Actin-Binding Protein Cortactin Modulate Cell Shape

Mark A. McNiven, Leung Kim, Eugene W. Krueger et al. · The Journal of Cell Biology · 2000 · 388 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Evidence that Mitotic Exit Is a Better Cancer Therapeutic Target Than Spindle Assembly

Hsiao-Chun Huang, Jue Shi, James D. Orth et al. · Cancer Cell · 2009 · 287 citations · Full text

Life Sciences, Cancer Biology, Oncology +12

Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction

James D. Orth, Alexander Loewer, Galit Lahav et al. · Molecular Biology of the Cell · 2011 · 256 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Cell Type Variation in Responses to Antimitotic Drugs that Target Microtubules and Kinesin-5

Jue Shi, James D. Orth, Tim Mitchison · Cancer Research · 2008 · 233 citations · Full text

Medicine, Oncology, Pharmacology +17

The large GTPase dynamin regulates actin comet formation and movement in living cells

James D. Orth, Eugene W. Krueger, Hong Cao et al. · Proceedings of the National Academy of Sciences · 2002 · 225 citations

Life Sciences, Cell Biology, Molecular Biology +15