Concepedia

Mitochondrial Priming

Mitochondrial Priming is a biochemical state in the intrinsic apoptotic pathway that denotes the proximity of a cell to the threshold of apoptosis, distinguished by the extent to which pro-apoptotic BCL-2 family proteins are engaged with anti-apoptotic counterparts, thereby determining cellular sensitivity to apoptotic stimuli.

37

Publications

4.4K

Citations

415

Authors

160

Institutions

Publications per year

2017–2026

19

Parents

Publications

37

Nix Is Critical to Two Distinct Phases of Mitophagy, Reactive Oxygen Species-mediated Autophagy Induction and Parkin-Ubiquitin-p62-mediated Mitochondrial Priming

Wen-Xing Ding, Hong-Min Ni, Min Li et al. · Journal of Biological Chemistry · 2010 · 587 citations · Full text

, , +17

Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy

Tríona Ní Chonghaile, Kristopher A. Sarosiek, Thanh-Trang T. Vo et al. · Science · 2011 · 587 citations

, , +17

Relative Mitochondrial Priming of Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML

Thanh‐Trang Vo, Jeremy Ryan, Ruben D. Carrasco et al. · Cell · 2012 · 339 citations · Full text

, , +14

SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages

Min‐Ji Kim, Soo Han Bae, Jae‐Chan Ryu et al. · Autophagy · 2016 · 291 citations · Full text

, , +17

Mitochondrial Priming by CD28

Ramon I. Klein Geltink, David O’Sullivan, Mauro Corrado et al. · Cell · 2017 · 283 citations · Full text

, , +11

1–5 of 37

Authors

415

  1. AL
    Anthony Letai

    Dana-Farber Cancer Institute, United States

    15 publications · 2.1K citations

    15

    h-index

  2. JR
    Jeremy Ryan

    Dana-Farber Cancer Institute, United States

    9 publications · 1.7K citations

    9

    h-index

  3. DJ
    Daniel J. DeAngelo

    Dana-Farber Cancer Institute, United States

    4 publications · 992 citations

    4

    h-index

  4. PB
    Patrick Bhola

    Dana-Farber Cancer Institute, United States

    3 publications · 313 citations

    3

    h-index

  5. MS
    Matthew S. Davids

    Dana-Farber Cancer Institute, United States

    3 publications · 166 citations

    3

    h-index

1–5 of 415

Institutions

160

  1. Dana-Farber Cancer Institute

    Boston, United States

    18 h-index

    133 publications

    21.2K citations

  2. Harvard University

    Cambridge, United States

    15 h-index

    78 publications

    7.8K citations

  3. Brigham and Women's Hospital

    Boston, United States

    6 h-index

    10 publications

    2K citations

  4. Broad Institute

    Cambridge, United States

    4 h-index

    6 publications

    294 citations

  5. University of California, San Francisco

    San Francisco, United States

    3 h-index

    8 publications

    193 citations

  6. Boston Children's Hospital

    Boston, United States

    3 h-index

    17 publications

    1.1K citations

  7. Harvard Stem Cell Institute

    Cambridge, United States

    3 h-index

    4 publications

    289 citations

  8. Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases

    Cologne, Germany

    2 h-index

    5 publications

    97 citations

1–8 of 160

Venues

  1. Cell Death and Disease

    4 publications · 206 citations

    4

    h-index

  2. Cell Death and Differentiation

    CDD · 3 publications · 160 citations

    3

    h-index

  3. Autophagy

    2 publications · 533 citations

    2

    h-index

  4. Haematologica

    2 publications · 34 citations

    2

    h-index

  5. Cell

    2 publications · 622 citations

    2

    h-index

1–5