Ruben D. Carrasco

A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance

Dharminder Chauhan, Ze Tian, Benjamin Nicholson et al. · Cancer Cell · 2012 · 575 citations

Hematological Malignancy, Malignant Blood Disorder, Apoptosis +10

Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages

Jennifer L. Guerriero, Alaba Sotayo, Holly Ponichtera et al. · Nature · 2017 · 540 citations · Full text

Breast Oncology, Medicine, Immunology +9

Bortezomib induces canonical nuclear factor-κB activation in multiple myeloma cells

Teru Hideshima, Hiroshi Ikeda, Dharminder Chauhan et al. · Blood · 2009 · 364 citations · Full text

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma

Samuel K. McBrayer, Jared R. Mayers, Gabriel J. DiNatale et al. · Cell · 2018 · 350 citations · Full text

Biochemistry, Medicine, Lipid Peroxidation +9

Relative Mitochondrial Priming of Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML

Thanh‐Trang Vo, Jeremy Ryan, Ruben D. Carrasco et al. · Cell · 2012 · 334 citations · Full text

Hematological Malignancy, Mixed-phenotype Acute Leukemia, Malignant Blood Disorder +9