Concepedia

Missing-self Recognition

Missing-Self Recognition is a theoretical immunological mechanism within the Major Histocompatibility Complex (MHC) paradigm in which natural killer cells detect the absence of self-MHC class I molecules on host cells, thereby distinguishing healthy cells from those that have undergone stress, infection, or transformation.

52

Publications

5.2K

Citations

348

Authors

123

Institutions

Publications per year

2017–2026

13

Parents

Publications

52

Combinations of Maternal KIR and Fetal HLA-C Genes Influence the Risk of Preeclampsia and Reproductive Success

Susan E. Hiby, James J. Walker, Kevin M. O’Shaughnessy et al. · The Journal of Experimental Medicine · 2004 · 1.1K citations · Full text

, , +17

Donor natural killer cell allorecognition of missing self in haploidentical hematopoietic transplantation for acute myeloid leukemia: challenging its predictive value.

Loredana Ruggeri, Antonella Mancusi, Marusca Capanni et al. · Blood · 2007 · 599 citations · Full text

, , +17

Ectopic expression of retinoic acid early inducible-1 gene (RAE-1) permits natural killer cell-mediated rejection of a MHC class I-bearing tumor <i>in vivo</i>

Adelheid Cerwenka, Jody L. Baron, Lewis L. Lanier · Proceedings of the National Academy of Sciences · 2001 · 594 citations · Full text

, , +15

MHC class I–specific inhibitory receptors and their ligands structure diverse human NK-cell repertoires toward a balance of missing self-response

Makoto Yawata, Nobuyo Yawata, Monia Draghi et al. · Blood · 2008 · 307 citations · Full text

, , +16

Natural killer cell recognition of missing self

Klas Kärre · Nature Immunology · 2008 · 282 citations

, , +10

1–5 of 52

Authors

348

  1. KK
    Klas Kärre

    Karolinska Institutet, Sweden

    6 publications · 576 citations

    6

    h-index

  2. PH
    Petter Höglund

    Karolinska Institutet, Sweden

    5 publications · 339 citations

    5

    h-index

  3. LL
    Lewis L. Lanier

    University of California, San Francisco, United States

    4 publications · 779 citations

    4

    h-index

  4. MH
    Maria H. Johansson

    Karolinska Institutet, Sweden

    4 publications · 198 citations

    4

    h-index

  5. WM
    Wayne M. Yokoyama

    Howard Hughes Medical Institute, United States

    4 publications · 137 citations

    4

    h-index

1–5 of 348

Institutions

123

  1. Karolinska Institutet

    Stockholm, Sweden

    11 h-index

    43 publications

    2.6K citations

  2. McGill University

    Montreal, Canada

    6 h-index

    10 publications

    548 citations

  3. University of California, San Francisco

    San Francisco, United States

    6 h-index

    12 publications

    2.2K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    15 publications

    4.9K citations

  5. Stanford University

    Stanford, United States

    3 h-index

    11 publications

    1.6K citations

  6. University of Ottawa

    Ottawa, Canada

    3 h-index

    17 publications

    792 citations

  7. Oslo University Hospital

    Oslo, Norway

    3 h-index

    14 publications

    746 citations

  8. Inserm

    Paris, France

    3 h-index

    10 publications

    470 citations

1–8 of 123

Venues

  1. The Journal of Immunology

    JI · 9 publications · 302 citations

    9

    h-index

  2. The Journal of Experimental Medicine

    7 publications · 1.7K citations

    7

    h-index

  3. Blood

    5 publications · 1.1K citations

    5

    h-index

  4. Frontiers in Immunology

    4 publications · 96 citations

    4

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 827 citations

    3

    h-index

1–5