Concepedia

Misfolding Intermediates

Misfolding Intermediates is a folding intermediate, distinguished by its adoption of non-native structural conformations that deviate from the productive folding pathway and may lead to aggregation or degradation rather than the functional native state.

39

Publications

2.9K

Citations

190

Authors

81

Institutions

Publications per year

2017–2026

5

Variants

Off-pathway Intermediates

Parents

Publications

39

Monomeric Cu,Zn-superoxide Dismutase Is a Common Misfolding Intermediate in the Oxidation Models of Sporadic and Familial Amyotrophic Lateral Sclerosis

Rishi Rakhit, John P. Crow, James R. Lepock et al. · Journal of Biological Chemistry · 2004 · 345 citations · Full text

, , +17

Identifying Unfolding Intermediates of FN-III10 by Steered Molecular Dynamics

Mu Gao, David W. Craig, Viola Vogel et al. · Journal of Molecular Biology · 2002 · 179 citations

, , +12

Cooperativity in Forced Unfolding of Tandem Spectrin Repeats

Richard Law, Philippe Carl, Sandy Harper et al. · Biophysical Journal · 2003 · 174 citations · Full text

, , +11

Quality control in the endoplasmic reticulum: folding and misfolding of vesicular stomatitis virus G protein in cells and in vitro.

A M de Silva, William E. Balch, Ari Helenius · The Journal of Cell Biology · 1990 · 151 citations · Full text

, , +17

Cooperative Assembly and Misfolding of CFTR Domains In Vivo

Kai Du, Gergely L. Lukács · Molecular Biology of the Cell · 2009 · 149 citations · Full text

, , +17

1–5 of 39

Authors

190

  1. JB
    Jayant B. Udgaonkar

    National Centre for Biological Sciences, India

    3 publications · 103 citations

    3

    h-index

  2. RB
    Robert B. Best

    National Institutes of Health, United States

    2 publications · 128 citations

    2

    h-index

  3. MM
    Miguel Machuqueiro

    University of Lisbon, Portugal

    2 publications · 134 citations

    2

    h-index

  4. AM
    António M. Baptista

    Universidade Nova de Lisboa, Portugal

    2 publications · 134 citations

    2

    h-index

  5. SG
    Stefano Gianni

    Istituto Pasteur, Italy

    2 publications · 69 citations

    2

    h-index

1–5 of 190

Institutions

81

  1. Tata Institute of Fundamental Research

    Mumbai, India

    3 h-index

    6 publications

    218 citations

  2. National Centre for Biological Sciences

    Bengaluru, India

    3 h-index

    7 publications

    258 citations

  3. University of Alberta

    Edmonton, Canada

    2 h-index

    13 publications

    1.4K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    2 h-index

    3 publications

    198 citations

  5. IBM (United States)

    Armonk, United States

    2 h-index

    8 publications

    632 citations

  6. KU Leuven

    Leuven, Belgium

    2 h-index

    8 publications

    385 citations

  7. Istituto Pasteur

    Rome, Italy

    2 h-index

    10 publications

    302 citations

  8. Center for Integrated Protein Science Munich

    Munich, Germany

    2 h-index

    8 publications

    660 citations

1–8 of 81

Venues

  1. Journal of Molecular Biology

    JMB · 5 publications · 301 citations

    5

    h-index

  2. Journal of Biological Chemistry

    JBC · 4 publications · 531 citations

    4

    h-index

  3. Biophysical Journal

    3 publications · 276 citations

    3

    h-index

  4. Structure

    3 publications · 168 citations

    3

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 295 citations

    3

    h-index

1–5