Methylation-based Tumor Classification

Methylation-Based Tumor Classification is a computational framework that categorizes tumor types and subtypes according to distinct patterns of DNA methylation profiles, leveraging epigenomic signatures as molecular fingerprints to distinguish neoplastic tissues beyond conventional histopathological or genetic criteria.

422

Publications

32.4K

Citations

4.5K

Authors

1.2K

Institutions

Publications per year

2017–2026

295

Parents

Dna Methylation Profiling

Publications

422

DNA methylation-based classification of central nervous system tumours

David Capper, David Jones, Martin Sill et al. · Nature · 2018 · 3.1K citations · Full text

Medicine, Molecular Genetics, Oncology +14

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

Katherine A. Hoadley, Christina Yau, Toshinori Hinoue et al. · Cell · 2018 · 2.7K citations · Full text

Medicine, Molecular Biology, Oncology +17

Sensitive tumour detection and classification using plasma cell-free DNA methylomes

Shu Yi Shen, Rajat Singhania, Gordon Fehringer et al. · Nature · 2018 · 1K citations · Full text

Medicine, Molecular Biology, Oncology +14

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

Felix Sahm, Daniel Schrimpf, Damian Stichel et al. · The Lancet Oncology · 2017 · 854 citations · Full text

Medicine, Molecular Biology, Pathology +16

High-throughput DNA methylation profiling using universal bead arrays

Marina Bibikova, Zhenwu Lin, Lixin Zhou et al. · Genome Research · 2006 · 673 citations

Medicine, Genetics, Molecular Biology +17

1–5 of 422

Authors

4.5K

AV
Andreas von Deimling
Heidelberg University, Germany
36 publications · 10.1K citations
30
h-index
SM
Stefan M. Pfister
Heidelberg University, Germany
32 publications · 7.7K citations
29
h-index
DC
David Capper
Heidelberg University, Germany
30 publications · 7.4K citations
26
h-index
DJ
David Jones
Heidelberg University, Germany
29 publications · 7.3K citations
25
h-index
MS
Martin Sill
German Cancer Research Center, Germany
20 publications · 6.7K citations
21
h-index

1–5 of 4.5K

Institutions

1.2K

1–8 of 1.2K

Venues

Neuro-Oncology
15 publications · 1K citations
15
h-index
Acta Neuropathologica
14 publications · 1.8K citations
15
h-index
Acta Neuropathologica Communications
15 publications · 819 citations
14
h-index
Clinical Epigenetics
11 publications · 504 citations
12
h-index
Clinical Cancer Research
10 publications · 608 citations
11
h-index

1–5