Concepedia

Metabolizing Enzyme Induction

Metabolizing Enzyme Induction is a biological phenomenon in which the expression and activity of drug-metabolizing enzymes are upregulated following exposure to specific xenobiotic or endogenous substrates, leading to enhanced metabolic capacity.

652

Publications

27.9K

Citations

2.4K

Authors

670

Institutions

Publications per year

2017–2026

40

Parents

Publications

652

Microbiota alteration is associated with the development of stress-induced despair behavior

Ioana Marin, Jennifer E. Goertz, Tiantian Ren et al. · Scientific Reports · 2017 · 377 citations · Full text

, , +17

27-Hydroxycholesterol Promotes Cell-Autonomous, ER-Positive Breast Cancer Growth

Qian Wu, Tomonori Ishikawa, Rosa Sirianni et al. · Cell Reports · 2013 · 355 citations · Full text

, , +14

Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes

Makiko Ohtsuji, Fumiki Katsuoka, Akira Kobayashi et al. · Journal of Biological Chemistry · 2008 · 319 citations · Full text

, , +14

Differential Induction of Prehepatic and Hepatic Metabolism of Verapamil by Rifampin

Martin F. Fromm, Dagmar Busse, H. Kroemer et al. · Hepatology · 1996 · 281 citations · Full text

, , +17

Enhancement of Glucuronide-Conjugating Capacity in a Hyperbilirubinemic Infant Due to Apparent Enzyme Induction by Phenobarbital

Sumner J. Yaffe, Gerhard Levy, Tai Matsuzawa et al. · New England Journal of Medicine · 1966 · 263 citations

, , +15

1–5 of 652

Authors

2.4K

  1. FO
    Franz Oesch

    Johannes Gutenberg University Mainz, Germany

    11 publications · 468 citations

    10

    h-index

  2. MS
    M.H. Siess

    Institut Agro Dijon, France

    6 publications · 252 citations

    6

    h-index

  3. MR
    Michael R. Franklin

    University of Utah, United States

    6 publications · 117 citations

    6

    h-index

  4. AS
    Akio Sato

    Tokyo Metropolitan Institute of Gerontology, Japan

    5 publications · 219 citations

    5

    h-index

  5. DW
    Daniel W. Nebert

    University of Cincinnati, United States

    5 publications · 192 citations

    5

    h-index

1–5 of 2.4K

Institutions

670

  1. University of Washington

    Seattle, United States

    12 h-index

    33 publications

    1.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    32 publications

    627 citations

  3. Inserm

    Paris, France

    10 h-index

    40 publications

    1.9K citations

  4. Johannes Gutenberg University Mainz

    Mainz, Germany

    10 h-index

    43 publications

    1.7K citations

  5. National Institutes of Health

    Bethesda, United States

    9 h-index

    22 publications

    1.7K citations

  6. Karolinska Institutet

    Stockholm, Sweden

    8 h-index

    21 publications

    964 citations

  7. University of Utah

    Salt Lake City, United States

    8 h-index

    18 publications

    436 citations

  8. National Institute of Environmental Health Sciences

    Durham, United States

    7 h-index

    13 publications

    471 citations

1–8 of 670

Venues

  1. PubMed

    Repository · 47 publications · 1.4K citations

    23

    h-index

  2. Drug Metabolism and Disposition

    28 publications · 1.3K citations

    22

    h-index

  3. Biochemical Pharmacology

    29 publications · 694 citations

    17

    h-index

  4. Toxicology and Applied Pharmacology

    TAAP · 19 publications · 954 citations

    16

    h-index

  5. British Journal of Clinical Pharmacology

    BJCP · 16 publications · 1.1K citations

    15

    h-index

1–5