Concepedia

Mesenteric Lymph Node Tolerance

Mesenteric Lymph Node Tolerance is a physiological mechanism of oral tolerance characterized by the preferential induction of antigen-specific immune unresponsiveness in T cells within the mesenteric lymph nodes, distinguishing it from systemic or other mucosal tolerance sites through its localization and dendritic cell-mediated regulation of gut-derived antigens.

57

Publications

3.9K

Citations

347

Authors

131

Institutions

Publications per year

2017–2026

10

Parents

Publications

57

Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells

Tim Worbs, Ulrike Bode, Sheng Yan et al. · The Journal of Experimental Medicine · 2006 · 697 citations · Full text

, , +16

Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells

Gera Goverse, Rosalie Molenaar, Laurence Macia et al. · The Journal of Immunology · 2017 · 196 citations · Full text

, , +17

Mesenteric lymph nodes are critical for the induction of high-dose oral tolerance in the absence of Peyer's patches

Thomas W. Spahn, Howard L. Weiner, Paul D. Rennert et al. · European Journal of Immunology · 2002 · 186 citations

, , +6

Production of immunity and unresponsiveness in the mouse by feeding contact sensitizing agents and the role of suppressor cells in the Peyer's patches, mesenteric lymph nodes and other lymphoid tissues

G L Asherson, Marek Zembala, M A Perera et al. · Cellular Immunology · 1977 · 173 citations

, , +16

Gastrointestinal Dendritic Cells Promote Th2 Skewing via OX40L

Ana-Belén Blázquez, M. Cecilia Berin · The Journal of Immunology · 2008 · 167 citations · Full text

, , +17

1–5 of 57

Authors

347

  1. HL
    Howard L. Weiner

    Brigham and Women's Hospital, United States

    5 publications · 440 citations

    5

    h-index

  2. PD
    Paul D. Rennert

    Biogen (United States), United States

    3 publications · 344 citations

    3

    h-index

  3. TW
    Thomas W. Spahn

    University of Münster, Germany

    3 publications · 344 citations

    3

    h-index

  4. JH
    Jochen Huehn

    Helmholtz Centre for Infection Research, Germany

    3 publications · 131 citations

    3

    h-index

  5. WR
    Wayne R. Thomas

    The Kids Research Institute Australia, Australia

    3 publications · 220 citations

    3

    h-index

1–5 of 347

Institutions

131

  1. Brigham and Women's Hospital

    Boston, United States

    4 h-index

    22 publications

    1.7K citations

  2. Harvard University

    Cambridge, United States

    4 h-index

    21 publications

    1.8K citations

  3. Inserm

    Paris, France

    4 h-index

    6 publications

    375 citations

  4. University of Glasgow

    Glasgow, United Kingdom

    4 h-index

    9 publications

    515 citations

  5. Medizinische Hochschule Hannover

    Hanover, Germany

    3 h-index

    7 publications

    1.8K citations

  6. Helmholtz Centre for Infection Research

    Braunschweig, Germany

    3 h-index

    22 publications

    1.3K citations

  7. Utrecht University

    Utrecht, The Netherlands

    3 h-index

    13 publications

    937 citations

  8. University of Gothenburg

    Gothenburg, Sweden

    3 h-index

    8 publications

    410 citations

1–8 of 131

Venues

  1. The Journal of Immunology

    JI · 9 publications · 674 citations

    9

    h-index

  2. European Journal of Immunology

    EJI · 7 publications · 609 citations

    7

    h-index

  3. PubMed

    Repository · 5 publications · 205 citations

    5

    h-index

  4. 2

    h-index

  5. Clinical & Experimental Allergy

    2 publications · 118 citations

    2

    h-index

1–5