Concepedia

Maximum Effect Models

Maximum Effect Model is a dose-response model in exposure-response analysis that characterizes the relationship between exposure level and biological response by assuming a saturable effect, where the response approaches an upper asymptote representing the maximum possible effect at high exposure levels.

47

Publications

2.4K

Citations

225

Authors

124

Institutions

Publications per year

2017–2026

9

Variants

Emax Models

Parents

Publications

47

Design aesthetics: principles of pleasure in design

Paul Hekkert · Research Repository (Delft University of Technology) · 2006 · 489 citations · Full text

, , +15

Remifentanil Versus Alfentanil

Talmage D. Egan, Charles F. Minto, David Hermann et al. · Anesthesiology · 1996 · 422 citations

, , +17

Retrospective population-based analysis of the dose-response (fecal fat excretion) relationship of orlistat in normal and obese volunteers

Jianguo Zhi, Angela T. Melia, Roberto Guerciolini et al. · Clinical Pharmacology & Therapeutics · 1994 · 281 citations

, , +16

Pharmacokinetic-pharmacodynamic modeling of activity of ceftazidime during continuous and intermittent infusion

Johan W. Mouton, Alexander A. Vinks, Nieko Punt · Antimicrobial Agents and Chemotherapy · 1997 · 139 citations · Full text

, , +14

Preclinical to Clinical Translation of Tofacitinib, a Janus Kinase Inhibitor, in Rheumatoid Arthritis

Martin E. Dowty, Michael I. Jesson, Sarbani Ghosh et al. · Journal of Pharmacology and Experimental Therapeutics · 2013 · 116 citations

, , +14

1–5 of 47

Authors

225

  1. RC
    Rik C. Schoemaker

    Centre for Human Drug Research, Netherlands

    2 publications · 80 citations

    2

    h-index

  2. PH
    Paul Hekkert

    Delft University of Technology, Netherlands

    2 publications · 506 citations

    2

    h-index

  3. DB
    David Back

    University of Liverpool, United Kingdom

    2 publications · 44 citations

    2

    h-index

  4. CF
    Clinton F. Stewart

    St. Jude Children's Research Hospital, United States

    2 publications · 193 citations

    2

    h-index

  5. TK
    Tatiana Khariton

    Institute for Clinical Pharmacodynamics (United States), United States

    2 publications · 35 citations

    2

    h-index

1–5 of 225

Institutions

124

  1. Centre for Human Drug Research

    Leiden, The Netherlands

    3 h-index

    10 publications

    349 citations

  2. Université Claude Bernard Lyon 1

    Villeurbanne, France

    3 h-index

    13 publications

    546 citations

  3. University of Liverpool

    Liverpool, United Kingdom

    3 h-index

    12 publications

    343 citations

  4. Erasmus MC

    Rotterdam, The Netherlands

    3 h-index

    10 publications

    608 citations

  5. Roche (Switzerland)

    Basel, Switzerland

    2 h-index

    9 publications

    2.1K citations

  6. Daiichi Sankyo (United States)

    Parsippany, United States

    2 h-index

    7 publications

    138 citations

  7. Inserm

    Paris, France

    2 h-index

    6 publications

    276 citations

  8. Hospices Civils de Lyon

    Lyon, France

    2 h-index

    7 publications

    174 citations

1–8 of 124

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 9 publications · 472 citations

    9

    h-index

  2. Clinical Pharmacology & Therapeutics

    CPT · 7 publications · 507 citations

    7

    h-index

  3. 2

    h-index

  4. British Journal of Clinical Pharmacology

    BJCP · 2 publications · 50 citations

    2

    h-index

  5. Clinical and Translational Science

    CTS · 2 publications · 33 citations

    2

    h-index

1–5