Jianguo Zhi

Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study

Isabelle Ray‐Coquard, Jean‐Yves Blay, Antoîne Italiano et al. · The Lancet Oncology · 2012 · 553 citations

Mdm2 Antagonist Rg7112, Medicine, Pharmacology +9

Results of the Phase I Trial of RG7112, a Small-Molecule MDM2 Antagonist in Leukemia

Michael Andreeff, Kevin R. Kelly, Karen Yee et al. · Clinical Cancer Research · 2015 · 344 citations · Full text

Retrospective population-based analysis of the dose-response (fecal fat excretion) relationship of orlistat in normal and obese volunteers

Jianguo Zhi, Angela T. Melia, Roberto Guerciolini et al. · Clinical Pharmacology & Therapeutics · 1994 · 280 citations

The Effect of Orlistat, an Inhibitor of Dietary Fat Absorption, on the Absorption of Vitamins A and E in Healthy Volunteers

Angela T. Melia, Susan G. Koss‐Twardy, Jianguo Zhi · The Journal of Clinical Pharmacology · 1996 · 115 citations

A Phase 1 study of RO6870810, a novel bromodomain and extra-terminal protein inhibitor, in patients with NUT carcinoma, other solid tumours, or diffuse large B-cell lymphoma

Geoffrey I. Shapiro, Patricia LoRusso, Afshin Dowlati et al. · British Journal of Cancer · 2020 · 115 citations · Full text