Concepedia

Matrix Rigidity Sensing

Matrix Rigidity Sensing is a cellular mechanotransduction process by which cells detect and respond to the mechanical stiffness of their surrounding extracellular matrix through force-dependent molecular interactions and cytoskeletal dynamics.

49

Publications

6K

Citations

271

Authors

123

Institutions

Publications per year

2017–2026

15

Parents

Publications

49

Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing

Masha Prager‐Khoutorsky, Alexandra Lichtenstein, Ramaswamy Krishnan et al. · Nature Cell Biology · 2011 · 570 citations

, , +16

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

Herbert B. Schiller, Michaela-Rosemarie Hermann, Julien Polleux et al. · Nature Cell Biology · 2013 · 424 citations

, , +17

Optimal matrix rigidity for stress-fibre polarization in stem cells

A. Zemel, Florian Rehfeldt, André EX Brown et al. · Nature Physics · 2010 · 382 citations · Full text

, , +16

Rigidity sensing and adaptation through regulation of integrin types

Alberto Elósegui-Artola, Elsa Bazellières, Michael D. Allen et al. · Nature Materials · 2014 · 377 citations · Full text

, , +14

Extracellular rigidity sensing by talin isoform-specific mechanical linkages

Katharina Austen, Pia Ringer, Alexander Mehlich et al. · Nature Cell Biology · 2015 · 358 citations

, , +14

1–5 of 49

Authors

271

  1. MP
    Michael P. Sheetz

    Columbia University, United States

    9 publications · 1.2K citations

    9

    h-index

  2. SL
    Shuaimin Liu

    Columbia University, United States

    5 publications · 781 citations

    5

    h-index

  3. HW
    Haguy Wolfenson

    Technion – Israel Institute of Technology, Israel

    5 publications · 587 citations

    5

    h-index

  4. PR
    Pere Roca‐Cusachs

    Institute for Bioengineering of Catalonia, Spain

    4 publications · 952 citations

    4

    h-index

  5. JH
    James Hone

    Columbia University, United States

    4 publications · 653 citations

    4

    h-index

1–5 of 271

Institutions

123

  1. National University of Singapore

    Singapore, Singapore

    9 h-index

    26 publications

    4.3K citations

  2. Columbia University

    New York, United States

    9 h-index

    52 publications

    7.5K citations

  3. Universitat de Barcelona

    Barcelona, Spain

    5 h-index

    12 publications

    1.7K citations

  4. Institute for Bioengineering of Catalonia

    Barcelona, Spain

    4 h-index

    9 publications

    2.8K citations

  5. Weizmann Institute of Science

    Rehovot, Israel

    4 h-index

    10 publications

    3.9K citations

  6. University of Michigan

    Ann Arbor, United States

    4 h-index

    13 publications

    1.3K citations

  7. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    7 publications

    672 citations

  8. University of Illinois Urbana-Champaign

    Urbana, United States

    3 h-index

    15 publications

    1.3K citations

1–8 of 123

Venues

  1. PLoS ONE

    5 publications · 453 citations

    5

    h-index

  2. Nature Cell Biology

    NCB · 4 publications · 1.6K citations

    4

    h-index

  3. Scientific Reports

    4 publications · 311 citations

    4

    h-index

  4. Journal of Cell Science

    3 publications · 294 citations

    3

    h-index

  5. Biomaterials

    3 publications · 159 citations

    3

    h-index

1–5