Concepedia

Marrow Failure Pathophysiology

Marrow Failure Pathophysiology is a pathophysiological framework that delineates the underlying mechanisms of impaired hematopoietic stem cell function and dysregulated bone marrow microenvironment leading to ineffective hematopoiesis and cytopenias in myelodysplastic syndromes.

346

Publications

18.1K

Citations

2K

Authors

592

Institutions

Publications per year

2017–2026

61

Parents

Publications

346

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia

Marc H.G.P. Raaijmakers, Siddhartha Mukherjee, Shangqin Guo et al. · Nature · 2010 · 1.1K citations

, , +13

Pure Red-Cell Aplasia of 10 Years' Duration Due to Persistent Parvovirus B19 Infection and Its Cure with Immunoglobulin Therapy

Gary J. Kurtzman, Norbert Frickhofen, Janice Kimball et al. · New England Journal of Medicine · 1989 · 433 citations

, , +17

Bone Marrow Failure in Fanconi Anemia Is Triggered by an Exacerbated p53/p21 DNA Damage Response that Impairs Hematopoietic Stem and Progenitor Cells

Raphaël Ceccaldi, Kalindi Parmar, Enguerran Mouly et al. · Cell stem cell · 2012 · 341 citations · Full text

, , +17

Interferon is a mediator of hematopoietic suppression in aplastic anemia in vitro and possibly in vivo.

Nicholas Zoumbos, Paula Herrero Gascon, J Y Djeu et al. · Proceedings of the National Academy of Sciences · 1985 · 340 citations · Full text

, , +10

Paroxysmal Nocturnal Hemoglobinuria Cells in Patients with Bone Marrow Failure Syndromes

Daniel E. Dunn, Patcharin Tanawattanacharoen, Piernicola Boccuni et al. · Annals of Internal Medicine · 1999 · 278 citations

, , +16

1–5 of 346

Authors

2K

  1. NS
    Neal S. Young

    National Heart Lung and Blood Institute, United States

    33 publications · 2.6K citations

    24

    h-index

  2. JP
    Jaroslaw P. Maciejewski

    Cleveland Clinic, United States

    10 publications · 669 citations

    10

    h-index

  3. JC
    Jichun Chen

    Chinese Academy of Medical Sciences & Peking Union Medical College, China

    10 publications · 529 citations

    10

    h-index

  4. SN
    Shinji Nakao

    Kanazawa University, Japan

    10 publications · 583 citations

    10

    h-index

  5. XF
    Xingmin Feng

    National Heart Lung and Blood Institute, United States

    9 publications · 410 citations

    9

    h-index

1–5 of 2K

Institutions

592

  1. National Heart Lung and Blood Institute

    Bethesda, United States

    25 h-index

    160 publications

    13.7K citations

  2. National Institutes of Health

    Bethesda, United States

    22 h-index

    133 publications

    6.5K citations

  3. University of Washington

    Seattle, United States

    12 h-index

    54 publications

    6K citations

  4. Harvard University

    Cambridge, United States

    11 h-index

    32 publications

    15.2K citations

  5. National Cancer Institute

    Bethesda, United States

    10 h-index

    24 publications

    751 citations

  6. Kanazawa University

    Kanazawa, Japan

    10 h-index

    61 publications

    3.6K citations

  7. The University of Texas MD Anderson Cancer Center

    Houston, United States

    10 h-index

    56 publications

    1.8K citations

  8. Boston Children's Hospital

    Boston, United States

    10 h-index

    21 publications

    1.5K citations

1–8 of 592

Venues

  1. Blood

    40 publications · 3.2K citations

    32

    h-index

  2. British Journal of Haematology

    BJH · 41 publications · 2K citations

    27

    h-index

  3. PubMed

    Repository · 30 publications · 904 citations

    18

    h-index

  4. Haematologica

    11 publications · 422 citations

    11

    h-index

  5. Journal of Clinical Investigation

    JCI · 11 publications · 807 citations

    11

    h-index

1–5