Concepedia

Macromolecular Complex Structure Determination

Macromolecular Complex Structure Determination is the process of elucidating the three-dimensional architecture of large biological assemblies at near-atomic resolution using cryo-electron microscopy, distinguished from other structural determination methods by its capacity to resolve dynamic, heterogeneous, and membrane-associated complexes in their native states.

370

Publications

30.9K

Citations

1.8K

Authors

572

Institutions

Publications per year

2017–2026

109

Parents

Publications

370

Structural and molecular interrogation of intact biological systems

Kwanghun Chung, Jenelle L. Wallace, Sung‐Yon Kim et al. · Nature · 2013 · 2.1K citations · Full text

, , +14

Atomic structures of respiratory complex III2, complex IV, and supercomplex III2-IV from vascular plants

María Maldonado, Fei Guo, James A. Letts · eLife · 2021 · 839 citations · Full text

, , +17

Structure of Subtilisin BPN′ at 2.5 Å Resolution

Christine Schubert Wright, Richard A. Alden, Joseph Kraut · Nature · 1969 · 541 citations

, , +11

Nuclear Pore Scaffold Structure Analyzed by Super-Resolution Microscopy and Particle Averaging

Anna Szymborska, Alex de Marco, Nathalie Daigle et al. · Science · 2013 · 478 citations

, , +17

2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor

Alberto Bartesaghi, Alan Merk, Soojay Banerjee et al. · Science · 2015 · 461 citations · Full text

, , +15

1–5 of 370

Authors

1.8K

  1. WB
    Wolfgang Baumeister

    Max Planck Institute of Biochemistry, Germany

    7 publications · 586 citations

    7

    h-index

  2. JL
    John L. Rubinstein

    University of Toronto, Canada

    6 publications · 632 citations

    6

    h-index

  3. MB
    Martin Beck

    European Molecular Biology Laboratory, Germany

    5 publications · 209 citations

    5

    h-index

  4. GJ
    Grant J. Jensen

    California Institute of Technology, United States

    5 publications · 349 citations

    5

    h-index

  5. NG
    Nikolaus Grigorieff

    Howard Hughes Medical Institute, United States

    5 publications · 266 citations

    5

    h-index

1–5 of 1.8K

Institutions

572

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    19 h-index

    50 publications

    7K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    17 h-index

    82 publications

    3.5K citations

  3. National Institutes of Health

    Bethesda, United States

    13 h-index

    49 publications

    7.4K citations

  4. Medical Research Council

    London, United Kingdom

    11 h-index

    36 publications

    4.3K citations

  5. Max Planck Institute of Biophysics

    Frankfurt am Main, Germany

    10 h-index

    47 publications

    2.6K citations

  6. The University of Osaka

    Osaka, Japan

    10 h-index

    30 publications

    3.7K citations

  7. University of Toronto

    Toronto, Canada

    10 h-index

    22 publications

    1.6K citations

  8. University of California, San Francisco

    San Francisco, United States

    10 h-index

    46 publications

    4.2K citations

1–8 of 572

Venues

  1. Journal of Molecular Biology

    JMB · 31 publications · 2.3K citations

    25

    h-index

  2. Journal of Biological Chemistry

    JBC · 24 publications · 1.5K citations

    23

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 18 publications · 2.1K citations

    17

    h-index

  4. Nature

    16 publications · 6.5K citations

    16

    h-index

  5. Nature Communications

    14 publications · 1.3K citations

    14

    h-index

1–5