Concepedia

Lysosomal Receptor Function

Lysosomal Receptor Function is a molecular mechanism within chaperone-mediated autophagy that specifically mediates the binding and translocation of cytosolic proteins bearing a KFERQ-like motif across the lysosomal membrane by recognizing and interacting with the lysosomal-associated membrane protein 2A (LAMP2A).

40

Publications

6.1K

Citations

162

Authors

60

Institutions

Publications per year

2017–2026

7

Parents

Publications

40

Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy

Ana María Cuervo, Leonidas Stefanis, Ross A. Fredenburg et al. · Science · 2004 · 2K citations

, , +17

Consequences of the selective blockage of chaperone-mediated autophagy

Ashish C. Massey, Susmita Kaushik, Guy Sovak et al. · Proceedings of the National Academy of Sciences · 2006 · 513 citations · Full text

, , +17

ClC-7 requires Ostm1 as a β-subunit to support bone resorption and lysosomal function

Philipp F. Lange, Lena Wartosch, Thomas J. Jentsch et al. · Nature · 2006 · 333 citations

, , +11

Degradation of  T Cell Receptor (TCR)–CD3-ζ Complexes after Antigenic Stimulation

Salvatore Valitutti, Sabina Müller, Mariolina Salio et al. · The Journal of Experimental Medicine · 1997 · 328 citations · Full text

, , +16

Inhibition of proteolytic degradation of low density lipoprotein in human fibroblasts by chloroquine, concanavalin A, and Triton WR 1339.

JL Goldstein, GY Brunschede, MS Brown · Journal of Biological Chemistry · 1975 · 311 citations · Full text

, , +17

1–5 of 40

Authors

162

  1. KW
    Keiji Wada

    National Center of Neurology and Psychiatry, Japan

    6 publications · 686 citations

    6

    h-index

  2. TK
    Tomohiro Kabuta

    National Center of Neurology and Psychiatry, Japan

    6 publications · 686 citations

    6

    h-index

  3. AM
    Ana María Cuervo

    Albert Einstein College of Medicine, United States

    5 publications · 3.2K citations

    5

    h-index

  4. YF
    Yuuki Fujiwara

    National Center of Neurology and Psychiatry, Japan

    4 publications · 420 citations

    4

    h-index

  5. SA
    Shu Aizawa

    National Center of Neurology and Psychiatry, Japan

    3 publications · 366 citations

    3

    h-index

1–5 of 162

Institutions

60

  1. National Center of Neurology and Psychiatry

    Tokyo, Japan

    6 h-index

    37 publications

    4.5K citations

  2. Albert Einstein College of Medicine

    Bronx, United States

    4 h-index

    19 publications

    14.4K citations

  3. Waseda University

    Tokyo, Japan

    3 h-index

    5 publications

    679 citations

  4. The University of Tokyo

    Tokyo, Japan

    2 h-index

    7 publications

    375 citations

  5. University of California San Diego

    San Diego, United States

    2 h-index

    10 publications

    708 citations

  6. Tufts University

    Medford, United States

    2 h-index

    3 publications

    787 citations

  7. Biogen (United States)

    Cambridge, United States

    2 h-index

    2 publications

    99 citations

  8. National Neuroscience Institute

    Singapore, Singapore

    2 h-index

    11 publications

    1.9K citations

1–8 of 60

Venues

  1. Journal of Biological Chemistry

    JBC · 6 publications · 868 citations

    6

    h-index

  2. Autophagy

    4 publications · 409 citations

    4

    h-index

  3. Biochemical and Biophysical Research Communications

    BBRC · 3 publications · 63 citations

    3

    h-index

  4. Journal of Cell Science

    2 publications · 512 citations

    2

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 562 citations

    2

    h-index

1–5