Concepedia

Lymphocyte Lineage Commitment

Lymphocyte Lineage Commitment is the developmental decision process by which multipotent hematopoietic progenitor cells become restricted to a specific lymphoid lineage, such as T cells, B cells, or natural killer cells, through the selective activation and repression of lineage-defining transcriptional programs.

196

Publications

21.8K

Citations

1.1K

Authors

323

Institutions

Publications per year

2017–2026

20

Parents

Publications

196

A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment

Susanne J. Szabo, Sean Kim, Gina L. Costa et al. · Cell · 2000 · 3.5K citations · Full text

, , +13

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

Stephen L. Nutt, Barry Heavey, Antonius Rolink et al. · Nature · 1999 · 1.2K citations

, , +14

Lineage commitment in the immune system: the T helper lymphocyte grows up

Laurie H. Glimcher, Kenneth M. Murphy · Genes & Development · 2000 · 621 citations · Full text

, , +17

Dicer Ablation Affects Antibody Diversity and Cell Survival in the B Lymphocyte Lineage

Sergei B. Koralov, Stefan A. Muljo, Gunther R. Galler et al. · Cell · 2008 · 570 citations · Full text

, , +16

T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow

Cécile Daussy, Fabrice Faure, Katia Mayol et al. · The Journal of Experimental Medicine · 2014 · 531 citations · Full text

, , +15

1–5 of 196

Authors

1.1K

  1. EV
    Ellen V. Rothenberg

    California Institute of Technology, United States

    10 publications · 1.2K citations

    10

    h-index

  2. MB
    Meinrad Busslinger

    Research Institute of Molecular Pathology, Austria

    6 publications · 1.9K citations

    6

    h-index

  3. HK
    Hiroshi Kawamoto

    Kyoto University, Japan

    4 publications · 535 citations

    4

    h-index

  4. DA
    David Allman

    University of Pennsylvania, United States

    4 publications · 556 citations

    4

    h-index

  5. BL
    Barbara L. Kee

    University of Chicago, United States

    4 publications · 176 citations

    4

    h-index

1–5 of 1.1K

Institutions

323

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    11 h-index

    26 publications

    3.5K citations

  2. Inserm

    Paris, France

    11 h-index

    76 publications

    10.9K citations

  3. Harvard University

    Cambridge, United States

    10 h-index

    35 publications

    18.5K citations

  4. University of Pennsylvania

    Philadelphia, United States

    10 h-index

    35 publications

    6.3K citations

  5. California Institute of Technology

    Pasadena, United States

    10 h-index

    45 publications

    5.1K citations

  6. Oklahoma Medical Research Foundation

    Oklahoma City, United States

    8 h-index

    27 publications

    1.3K citations

  7. University of Chicago

    Chicago, United States

    7 h-index

    22 publications

    2.3K citations

  8. Memorial Sloan Kettering Cancer Center

    New York, United States

    7 h-index

    55 publications

    5.4K citations

1–8 of 323

Venues

  1. Blood

    27 publications · 2.3K citations

    24

    h-index

  2. The Journal of Immunology

    JI · 28 publications · 1.3K citations

    21

    h-index

  3. The Journal of Experimental Medicine

    16 publications · 2K citations

    16

    h-index

  4. Immunity

    13 publications · 1.4K citations

    13

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 1.3K citations

    12

    h-index

1–5