Concepedia

Lymphatic Valve Dysfunction

Lymphatic Valve Dysfunction is a pathophysiological condition characterized by impaired structural or functional integrity of intraluminal valves within lymphatic vessels, resulting in defective unidirectional lymph flow and predisposing to lymphatic fluid accumulation.

22

Publications

2.7K

Citations

159

Authors

83

Institutions

Publications per year

2017–2026

7

Parents

Publications

22

Defective valves and abnormal mural cell recruitment underlie lymphatic vascular failure in lymphedema distichiasis

Tatiana V. Petrova, Terhi Kärpänen, Camilla Norrmén et al. · Nature Medicine · 2004 · 591 citations

, , +11

Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation

Keiko Nonomura, Viktor Lukacs, Daniel T. Sweet et al. · Proceedings of the National Academy of Sciences · 2018 · 270 citations · Full text

, , +17

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature

Amélie Sabine, Esther Bovay, Cansaran Saygili Demir et al. · Journal of Clinical Investigation · 2015 · 233 citations · Full text

, , +17

Mutations in <i>FOXC2</i> Are Strongly Associated With Primary Valve Failure in Veins of the Lower Limb

Russell H. Mellor, Glen Brice, A.W.B. Stanton et al. · Circulation · 2007 · 212 citations · Full text

, , +16

Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax

John D. Kanady, Michael T. Dellinger, Stephanie J. Munger et al. · Developmental Biology · 2011 · 179 citations

, , +14

1–5 of 22

Authors

159

  1. TV
    Tatiana V. Petrova

    University of Lausanne, Switzerland

    4 publications · 1K citations

    4

    h-index

  2. MJ
    Michael J. Davis

    University of Missouri, United States

    4 publications · 378 citations

    4

    h-index

  3. KA
    Kari Alitalo

    University of Helsinki, Finland

    3 publications · 897 citations

    3

    h-index

  4. PM
    Peter Mortimer

    St George's, University of London, United Kingdom

    3 publications · 844 citations

    3

    h-index

  5. AM
    Alexander M. Simon

    University of Arizona, United States

    3 publications · 248 citations

    3

    h-index

1–5 of 159

Institutions

83

  1. University of Missouri

    Columbia, United States

    5 h-index

    7 publications

    666 citations

  2. University Hospital of Lausanne

    Lausanne, Switzerland

    3 h-index

    12 publications

    2K citations

  3. Hamamatsu University School of Medicine

    Hamamatsu, Japan

    3 h-index

    20 publications

    4K citations

  4. University of Arizona

    Tucson, United States

    3 h-index

    8 publications

    1K citations

  5. École Polytechnique Fédérale de Lausanne

    Lausanne, Switzerland

    2 h-index

    2 publications

    363 citations

  6. University of Helsinki

    Helsinki, Finland

    2 h-index

    11 publications

    3.3K citations

  7. Oklahoma Medical Research Foundation

    Oklahoma City, United States

    2 h-index

    3 publications

    364 citations

  8. Helsinki University Hospital

    Helsinki, Finland

    2 h-index

    5 publications

    2.5K citations

1–8 of 83

Venues

  1. Journal of Clinical Investigation

    JCI · 4 publications · 635 citations

    4

    h-index

  2. Developmental Biology

    2 publications · 224 citations

    2

    h-index

  3. Immunity

    1 publications · 76 citations

    1

    h-index

  4. Nature Communications

    1 publications · 88 citations

    1

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 1 publications · 270 citations

    1

    h-index

1–5