Concepedia

Long-range Regulatory Interactions

Long-Range Regulatory Interactions is a genetic regulatory phenomenon in which distal genomic elements, such as enhancers or silencers, physically interact with target gene promoters through three-dimensional chromatin looping to modulate transcriptional activity across large genomic distances.

155

Publications

17.8K

Citations

1K

Authors

372

Institutions

Publications per year

2017–2026

56

Variants

Long-range Chromatin Interactions

Parents

Publications

155

The long-range interaction landscape of gene promoters

Amartya Sanyal, Bryan R. Lajoie, Gaurav Jain et al. · Nature · 2012 · 1.5K citations · Full text

, , +17

Ensembl 2016

Andrew Yates, Wasiu Akanni, M Ridwan Amode et al. · Nucleic Acids Research · 2015 · 1.4K citations · Full text

, , +16

The topology of the regulatory interactions predicts the expression pattern of the segment polarity genes in Drosophila melanogaster

Réka Albert, Hans G. Othmer · Journal of Theoretical Biology · 2003 · 967 citations · Full text

, , +16

Controlling Long-Range Genomic Interactions at a Native Locus by Targeted Tethering of a Looping Factor

Wulan Deng, Jongjoo Lee, Hong‐Xin Wang et al. · Cell · 2012 · 756 citations

, , +14

Transcriptome-wide Analysis of Regulatory Interactions of the RNA-Binding Protein HuR

Svetlana Lebedeva, Marvin Jens, Kathrin Theil et al. · Molecular Cell · 2011 · 746 citations · Full text

, , +15

1–5 of 155

Authors

1K

  1. PF
    Peter Fraser

    Babraham Institute, United Kingdom

    8 publications · 2.1K citations

    8

    h-index

  2. PF
    Paul Flicek

    European Bioinformatics Institute, United Kingdom

    5 publications · 1.8K citations

    5

    h-index

  3. JD
    Job Dekker

    University of Massachusetts Chan Medical School, United States

    5 publications · 2.1K citations

    5

    h-index

  4. SS
    Stefan Schoenfelder

    Babraham Institute, United Kingdom

    5 publications · 1.4K citations

    5

    h-index

  5. BL
    Boris Lenhard

    University of Bergen, Norway

    4 publications · 747 citations

    4

    h-index

1–5 of 1K

Institutions

372

  1. Babraham Institute

    Cambridge, United Kingdom

    9 h-index

    9 publications

    2.2K citations

  2. European Bioinformatics Institute

    Cambridge, United Kingdom

    8 h-index

    8 publications

    2.5K citations

  3. National Institutes of Health

    Bethesda, United States

    8 h-index

    8 publications

    1.6K citations

  4. University of Pennsylvania

    Philadelphia, United States

    7 h-index

    7 publications

    1.3K citations

  5. Wellcome Sanger Institute

    Cambridge, United Kingdom

    6 h-index

    6 publications

    1.9K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    5 publications

    270 citations

  7. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    5 publications

    502 citations

  8. University of Massachusetts Chan Medical School

    Worcester, United States

    5 h-index

    5 publications

    2.1K citations

1–8 of 372

Venues

  1. Nucleic Acids Research

    15 publications · 2.7K citations

    15

    h-index

  2. Nature Communications

    11 publications · 1.3K citations

    11

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 9 publications · 507 citations

    9

    h-index

  4. Genome Research

    GR · 8 publications · 1.4K citations

    8

    h-index

  5. Cell Reports

    6 publications · 516 citations

    6

    h-index

1–5