Concepedia

Loading Efficiency Optimization

Loading Efficiency Optimization is a methodological framework in pharmaceutical formulation science that systematically enhances the proportion of a drug successfully incorporated into a delivery system relative to the initial quantity used, distinguished by its focus on maximizing encapsulation efficacy through precise control of physicochemical parameters and process conditions.

88

Publications

3.3K

Citations

422

Authors

161

Institutions

Publications per year

2017–2026

38

Parents

Publications

88

High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: Quality by design optimization and characterization

Dongmei Cun, Ditte Krohn Jensen, Morten Jonas Maltesen et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2010 · 233 citations

, , +16

Syringe loading introduces macromolecules into living mammalian cell cytosol

Mark S. F. Clarke, Paul L. McNeil · Journal of Cell Science · 1992 · 121 citations · Full text

, , +13

High loading efficiency and tunable release of plasmid DNA encapsulated in submicron particles fabricated from PLGA conjugated with poly-L-lysine

Jeremy S. Blum, W. Mark Saltzman · Journal of Controlled Release · 2008 · 107 citations · Full text

, , +16

Plant‐Based Hollow Microcapsules for Oral Delivery Applications: Toward Optimized Loading and Controlled Release

Michael G. Potroz, Raghavendra C. Mundargi, J. J. J. Gillissen et al. · Advanced Functional Materials · 2017 · 106 citations

, , +17

Preparation and Characterization of Novel Functionalized Prochloraz Microcapsules Using Silica–Alginate–Elements as Controlled Release Carrier Materials

Wenbing Zhang, Shun He, Yao Liu et al. · ACS Applied Materials & Interfaces · 2014 · 103 citations

, , +15

1–5 of 88

Authors

422

  1. TU
    Takahiro Uchida

    Mukogawa Women's University, Japan

    3 publications · 129 citations

    3

    h-index

  2. TR
    Tatiana Rocío Aguirre‐Calvo

    Universidad de Buenos Aires, Argentina

    2 publications · 34 citations

    2

    h-index

  3. LY
    Le Yu

    Northwest University, China

    2 publications · 27 citations

    2

    h-index

  4. KY
    Kazushi Yoshida

    Panasonic (Japan), Japan

    2 publications · 73 citations

    2

    h-index

  5. MK
    Md. Khalid Anwer

    Prince Sattam Bin Abdulaziz University, Saudi Arabia

    2 publications · 50 citations

    2

    h-index

1–5 of 422

Institutions

161

  1. University of Chinese Academy of Sciences

    Beijing, China

    3 h-index

    12 publications

    634 citations

  2. Misr University for Science and Technology

    Cairo, Egypt

    3 h-index

    6 publications

    144 citations

  3. Sichuan University

    Chengdu, China

    3 h-index

    7 publications

    217 citations

  4. Ocean University of China

    Qingdao, China

    2 h-index

    13 publications

    175 citations

  5. Hanyang University

    Seoul, South Korea

    2 h-index

    5 publications

    180 citations

  6. Zagazig University

    Zagazig, Egypt

    2 h-index

    3 publications

    66 citations

  7. Harvard University

    Cambridge, United States

    2 h-index

    7 publications

    692 citations

  8. Consejo Nacional de Investigaciones Científicas y Técnicas

    Buenos Aires, Argentina

    2 h-index

    8 publications

    136 citations

1–8 of 161

Venues

  1. Journal of Microencapsulation

    4 publications · 139 citations

    4

    h-index

  2. Polymers

    3 publications · 82 citations

    3

    h-index

  3. Chemical and Pharmaceutical Bulletin

    3 publications · 129 citations

    3

    h-index

  4. Drug Development and Industrial Pharmacy

    3 publications · 50 citations

    3

    h-index

  5. Drug Delivery

    3 publications · 65 citations

    3

    h-index

1–5