Concepedia

Liver Compartment Models

Liver Compartment Models is a type of physiologically based pharmacokinetic model that specifically represents the liver as a distinct compartment to characterize the organ's role in drug metabolism and clearance within the systemic circulation.

35

Publications

1.3K

Citations

130

Authors

64

Institutions

Publications per year

2017–2026

3

Parents

Publications

35

A linear method for determining liver sinusoidal and extravascular volumes

Carl A. Goresky · American Journal of Physiology-Legacy Content · 1963 · 396 citations

, , +15

A cell culture analogue of rodent physiology: Application to naphthalene toxicology

Lisa Sweeney, Michael L. Shuler, John G. Babish et al. · Toxicology in Vitro · 1995 · 85 citations · Full text

, , +17

Mechanistic Modeling of Hepatic Transport from Cells to Whole Body: Application to Napsagatran and Fexofenadine

Agnès Poirier, Christoph Funk, Jean‐Michel Scherrmann et al. · Molecular Pharmaceutics · 2009 · 61 citations

, , +17

Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism

Marieke G. Schooneman, Gabriëlla A. M. Ten Have, Naomi van Vlies et al. · American Journal of Physiology-Endocrinology and Metabolism · 2015 · 57 citations · Full text

, , +14

Local and Global Function Model of the Liver

Hesheng Wang, Mary Feng, Andrew Jackson et al. · International Journal of Radiation Oncology*Biology*Physics · 2015 · 47 citations · Full text

, , +10

1–5 of 35

Authors

130

  1. DC
    Dennis Coombe

    Virtual Materials Group (Canada), Canada

    2 publications · 58 citations

    2

    h-index

  2. RK
    Randall K. Ten Haken

    University of Michigan, United States

    2 publications · 59 citations

    2

    h-index

  3. TS
    Theodore S. Lawrence

    University of Michigan, United States

    2 publications · 59 citations

    2

    h-index

  4. GM
    G Molino

    University of Turin, Italy

    2 publications · 60 citations

    2

    h-index

  5. VR
    Vahid Rezania

    University of Alberta, Canada

    2 publications · 58 citations

    2

    h-index

1–5 of 130

Institutions

64

  1. Virtual Materials Group (Canada)

    Calgary, Canada

    2 h-index

    2 publications

    58 citations

  2. Erasmus University Rotterdam

    Rotterdam, The Netherlands

    2 h-index

    11 publications

    309 citations

  3. University of Michigan

    Ann Arbor, United States

    2 h-index

    11 publications

    307 citations

  4. University of Alberta

    Edmonton, Canada

    2 h-index

    4 publications

    126 citations

  5. MacEwan University

    Edmonton, Canada

    2 h-index

    2 publications

    58 citations

  6. Inserm

    Paris, France

    1 h-index

    4 publications

    244 citations

  7. Cornell University

    Ithaca, United States

    1 h-index

    4 publications

    340 citations

  8. Institut national de recherche en sciences et technologies du numérique

    Le Chesnay-Rocquencourt, France

    1 h-index

    4 publications

    68 citations

1–8 of 64

Venues

  1. Toxicological Sciences

    2 publications · 63 citations

    2

    h-index

  2. Chemical and Pharmaceutical Bulletin

    2 publications · 47 citations

    2

    h-index

  3. Endocrinology

    2 publications · 54 citations

    2

    h-index

  4. Drug Metabolism and Disposition

    2 publications · 46 citations

    2

    h-index

  5. PubMed

    Repository · 2 publications · 45 citations

    2

    h-index

1–5