Michael L. Shuler

A guide to the organ-on-a-chip

Chak Ming Leung, Pim de Haan, Kacey Ronaldson-Bouchard et al. · Nature Reviews Methods Primers · 2022 · 1K citations · Full text

Engineering, Bioengineering, Biomedical Engineering +15

Microfluidic blood–brain barrier model provides in vivo‐like barrier properties for drug permeability screening

Ying I. Wang, Hasan Erbil Abaci, Michael L. Shuler · Biotechnology and Bioengineering · 2016 · 563 citations · Full text

Engineering, Biomedical Engineering, Neuroscience +17

A microfluidic device for a pharmacokinetic–pharmacodynamic (PK–PD) model on a chip

Jong Hwan Sung, Carrie Kam, Michael L. Shuler · Lab on a Chip · 2010 · 477 citations

Engineering, Biomedical Engineering, Pharmacology +17

A micro cell culture analog (µCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs

Jong Hwan Sung, Michael L. Shuler · Lab on a Chip · 2009 · 434 citations

Medicine, Bioengineering, Oncology +17

Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs

Carlota Oleaga, Catia Bernabini, Alec S.T. Smith et al. · Scientific Reports · 2016 · 425 citations · Full text

Pharmacy, Pharmacology, Toxicology +17