Concepedia

Ligand-based Interaction Screening

Ligand-Based Interaction Screening is a computational approach within interaction screening that identifies potential molecular interactions by analyzing the structural and physicochemical properties of known ligands, without requiring prior knowledge of the target's structure.

61

Publications

3.1K

Citations

326

Authors

150

Institutions

Publications per year

2017–2026

21

Parents

Publications

61

One-Dimensional Relaxation- and Diffusion-Edited NMR Methods for Screening Compounds That Bind to Macromolecules

Philip J. Hajduk, Edward T. Olejniczak, Stephen W. Fesik · Journal of the American Chemical Society · 1997 · 368 citations

, , +17

Saturation-Transfer Difference (STD) NMR: A Simple and Fast Method for Ligand Screening and Characterization of Protein Binding

Aldino Viegas, João Manso, Franklin L. Nóbrega et al. · Journal of Chemical Education · 2011 · 314 citations

, , +17

High-Throughput NMR-Based Screening with Competition Binding Experiments

Claudio Dalvit, Maria M. Flocco, Stefan Knapp et al. · Journal of the American Chemical Society · 2002 · 154 citations

, , +16

Analysis of small-molecule interactions using Biacore S51 technology

David G. Myszka · Analytical Biochemistry · 2004 · 146 citations

, , +9

NMR-Based Screening with Competition Water−Ligand Observed via Gradient Spectroscopy Experiments:  Detection of High-Affinity Ligands

Claudio Dalvit, Marina Fasolini, Maria M. Flocco et al. · Journal of Medicinal Chemistry · 2002 · 116 citations

, , +16

1–5 of 61

Authors

326

  1. CD
    Claudio Dalvit

    Novartis (Switzerland), Switzerland

    3 publications · 312 citations

    3

    h-index

  2. SK
    Stefan Knapp

    University of Oxford, United Kingdom

    2 publications · 270 citations

    2

    h-index

  3. MM
    Maria M. Flocco

    Nerviano Medical Sciences, Italy

    2 publications · 270 citations

    2

    h-index

  4. MV
    Marina Veronesi

    Italian Institute of Technology, Italy

    2 publications · 270 citations

    2

    h-index

  5. EL
    Emma-Louise Lyle

    University of Toronto, Canada

    1 publications · 26 citations

    1

    h-index

1–5 of 326

Institutions

150

  1. King Saud University

    Riyadh, Saudi Arabia

    4 h-index

    13 publications

    621 citations

  2. Roche (Switzerland)

    Basel, Switzerland

    2 h-index

    9 publications

    387 citations

  3. Université de Strasbourg

    Strasbourg, France

    2 h-index

    6 publications

    114 citations

  4. Council of Scientific and Industrial Research

    New Delhi, India

    2 h-index

    12 publications

    429 citations

  5. Inserm

    Paris, France

    2 h-index

    6 publications

    411 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    16 publications

    402 citations

  7. National University of Singapore

    Singapore, Singapore

    2 h-index

    9 publications

    465 citations

  8. Mansoura University

    Al Mansurah, Egypt

    2 h-index

    4 publications

    149 citations

1–8 of 150

Venues

  1. PLoS ONE

    4 publications · 139 citations

    4

    h-index

  2. Analytical Biochemistry

    4 publications · 250 citations

    4

    h-index

  3. Analytical Chemistry

    3 publications · 144 citations

    3

    h-index

  4. Journal of the American Chemical Society

    JACS · 3 publications · 541 citations

    3

    h-index

  5. Journal of Molecular Structure

    3 publications · 140 citations

    3

    h-index

1–5