Concepedia

Licensing Inhibition

Licensing Inhibition is a regulatory mechanism in DNA replication that functions as a checkpoint control preventing the re-assembly of pre-replicative complexes on already replicated DNA, thereby ensuring each segment of the genome is duplicated exactly once per cell cycle.

16

Publications

1.1K

Citations

106

Authors

51

Institutions

Publications per year

2017–2026

3

Variants

Replication Licensing Inhibition

Parents

Publications

16

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Panagiotis Galanos, Konstantinos Vougas, David Walter et al. · Nature Cell Biology · 2016 · 312 citations · Full text

, , +16

Cell type-specific responses of human cells to inhibition of replication licensing

Sathyavageeswaran Shreeram, Alison Sparks, David P. Lane et al. · Oncogene · 2002 · 175 citations

, , +16

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin

Changwook Lee, Bum‐Soo Hong, Jung Min Choi et al. · Nature · 2004 · 147 citations

, , +12

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

Valeria De Marco, Peter J. Gillespie, A. Li et al. · Proceedings of the National Academy of Sciences · 2009 · 81 citations · Full text

, , +17

Origin licensing and p53 status regulate Cdk2 activity during G1

Kathleen R. Nevis, Marila Cordeiro‐Stone, Jeanette Gowen Cook · Cell Cycle · 2009 · 76 citations · Full text

, , +17

1–5 of 16

Authors

106

  1. JJ
    J. Julian Blow

    University of Dundee, United Kingdom

    4 publications · 590 citations

    4

    h-index

  2. EJ
    Emma J. Haagensen

    Newcastle University, United Kingdom

    2 publications · 334 citations

    2

    h-index

  3. YC
    Yunje Cho

    Pohang University of Science and Technology, South Korea

    2 publications · 158 citations

    2

    h-index

  4. ST
    Shusuke Tada

    Tohoku University, Japan

    2 publications · 158 citations

    2

    h-index

  5. PJ
    Peter J. Gillespie

    University of Dundee, United Kingdom

    2 publications · 103 citations

    2

    h-index

1–5 of 106

Institutions

51

  1. University of Dundee

    Dundee, United Kingdom

    4 h-index

    18 publications

    1.8K citations

  2. The University of Osaka

    Osaka, Japan

    2 h-index

    7 publications

    215 citations

  3. University of Patras

    Pátrai, Greece

    2 h-index

    6 publications

    352 citations

  4. Pohang University of Science and Technology

    Pohang, South Korea

    2 h-index

    7 publications

    893 citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    5 publications

    204 citations

  6. Wellcome Trust

    London, United Kingdom

    2 h-index

    5 publications

    593 citations

  7. Tohoku University

    Sendai, Japan

    2 h-index

    9 publications

    507 citations

  8. Karolinska Institutet

    Stockholm, Sweden

    1 h-index

    1 publications

    312 citations

1–8 of 51

Venues

  1. Genes to Cells

    2 publications · 67 citations

    2

    h-index

  2. Oncogene

    1 publications · 175 citations

    1

    h-index

  3. Journal of Cellular Biochemistry

    1 publications · 23 citations

    1

    h-index

  4. Nature Cell Biology

    NCB · 1 publications · 312 citations

    1

    h-index

  5. Journal of Cell Science

    1 publications · 30 citations

    1

    h-index

1–5