Concepedia

Library Diversification

Library Diversification is a methodological process in molecular engineering that generates variant libraries of nucleic acid sequences through controlled recombination, mutation, or synthetic design to enhance the genetic diversity available for functional screening within directed evolution pipelines.

23

Publications

905

Citations

102

Authors

33

Institutions

Publications per year

2017–2026

8

Parents

Publications

23

The Effectiveness of Reactant Pools for Generating Structurally-Diverse Combinatorial Libraries

Valerie J. Gillet, Peter Willett, John Bradshaw · Journal of Chemical Information and Computer Sciences · 1997 · 146 citations

, , +16

Incorporating Synthetic Oligonucleotides via Gene Reassembly (ISOR): a versatile tool for generating targeted libraries

Asael Herman, Dan S. Tawfik · Protein Engineering Design and Selection · 2007 · 108 citations · Full text

, , +17

Inhibiting HER3-Mediated Tumor Cell Growth with Affibody Molecules Engineered to Low Picomolar Affinity by Position-Directed Error-Prone PCR-Like Diversification

Magdalena Malm, Nina Kronqvist, Hanna Lindberg et al. · PLoS ONE · 2013 · 73 citations · Full text

, , +14

A deconstruction–reconstruction strategy for pyrimidine diversification

Benjamin J. H. Uhlenbruck, Celena M. Josephitis, Louis de Lescure et al. · Nature · 2024 · 71 citations · Full text

, , +8

Hydrazone- and Hydrazide-Containing <i>N</i>-Substituted Glycines as Peptoid Surrogates for Expedited Library Synthesis:  Application to the Preparation of Tsg101-Directed HIV-1 Budding Antagonists

Fa Liu, Andrew G. Stephen, Catherine S. Adamson et al. · Organic Letters · 2006 · 44 citations · Full text

, , +17

1–5 of 23

Authors

102

  1. MW
    Marvin Waldman

    Simulations Plus (United States), United States

    2 publications · 48 citations

    2

    h-index

  2. DS
    Dan S. Tawfik

    Weizmann Institute of Science, Israel

    2 publications · 120 citations

    2

    h-index

  3. MH
    Moises Hassan

    Simulations Plus (United States), United States

    2 publications · 48 citations

    2

    h-index

  4. JG
    Jinhai Gao

    Northeastern University, China

    1 publications · 20 citations

    1

    h-index

  5. XS
    Xianli Shu

    Fuzhou University, China

    1 publications · 38 citations

    1

    h-index

1–5 of 102

Institutions

33

  1. Simulations Plus (United States)

    Lancaster, United States

    2 h-index

    6 publications

    144 citations

  2. Weizmann Institute of Science

    Rehovot, Israel

    2 h-index

    5 publications

    252 citations

  3. Center for Systems Biology

    Boston, United States

    1 h-index

    1 publications

    14 citations

  4. Science Applications International Corporation (United States)

    McLean, United States

    1 h-index

    8 publications

    352 citations

  5. Universiti Sains Malaysia

    George Town, Malaysia

    1 h-index

    4 publications

    88 citations

  6. University of Wisconsin Carbone Cancer Center

    Madison, United States

    1 h-index

    1 publications

    19 citations

  7. University of Cambridge

    Cambridge, United Kingdom

    1 h-index

    4 publications

    124 citations

  8. KTH Royal Institute of Technology

    Stockholm, Sweden

    1 h-index

    6 publications

    438 citations

1–8 of 33

Venues

  1. Organic Letters

    OL · 2 publications · 87 citations

    2

    h-index

  2. Protein Engineering Design and Selection

    PEDS · 2 publications · 149 citations

    2

    h-index

  3. Journal of Molecular Graphics and Modelling

    2 publications · 48 citations

    2

    h-index

  4. Angewandte Chemie International Edition

    2 publications · 38 citations

    2

    h-index

  5. Methods in molecular biology

    Book series · 1 publications · 12 citations

    1

    h-index

1–5