Concepedia

Lepr Mutations

LEPR Mutations is a genetic alteration in the leptin receptor gene that disrupts leptin signaling and is associated with monogenic forms of obesity and pubertal development disorders.

211

Publications

10.9K

Citations

1.6K

Authors

624

Institutions

Publications per year

2017–2026

43

Variants

Lepr Gene Mutations

Parents

Publications

211

Binge Eating as a Major Phenotype of Melanocortin 4 Receptor Gene Mutations

Ruth Branson, Natascha Potoczna, John G. Kral et al. · New England Journal of Medicine · 2003 · 374 citations

, , +13

Leptin Mediates the Increase in Blood Pressure Associated with Obesity

Stephanie E. Simonds, Jack T. Pryor, Éric Ravussin et al. · Cell · 2014 · 346 citations · Full text

, , +13

Regulation of<i>Fto/Ftm</i>gene expression in mice and humans

George Stratigopoulos, Stéphanie L. Padilla, Charles A. LeDuc et al. · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · 2008 · 329 citations

, , +14

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

Seongjin Seo, Deng‐Fu Guo, Kevin Bugge et al. · Human Molecular Genetics · 2009 · 321 citations · Full text

, , +14

Prevalence of mutations in LEP, LEPR, and MC4R genes in individuals with severe obesity

Barbara Paolini, Paolo Enrico Maltese, Irene Del Ciondolo et al. · Genetics and Molecular Research · 2016 · 308 citations · Full text

, , +12

1–5 of 211

Authors

1.6K

  1. RL
    Rudolph L. Leibel

    Columbia University, United States

    15 publications · 2.1K citations

    15

    h-index

  2. SC
    Streamson C. Chua

    Albert Einstein College of Medicine, United States

    11 publications · 1.3K citations

    11

    h-index

  3. MG
    Martin G. Myers

    University of Michigan, United States

    7 publications · 385 citations

    7

    h-index

  4. WK
    Wendy K. Chung

    Columbia University, United States

    4 publications · 775 citations

    4

    h-index

  5. OU
    Olavi Ukkola

    University of Oulu, Finland

    4 publications · 166 citations

    4

    h-index

1–5 of 1.6K

Institutions

624

  1. Columbia University

    New York, United States

    13 h-index

    38 publications

    4.1K citations

  2. Inserm

    Paris, France

    7 h-index

    44 publications

    2.3K citations

  3. University of Michigan

    Ann Arbor, United States

    7 h-index

    14 publications

    906 citations

  4. Pennington Biomedical Research Center

    Baton Rouge, United States

    6 h-index

    17 publications

    1.8K citations

  5. Jackson Laboratory

    Bar Harbor, United States

    6 h-index

    24 publications

    1.3K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    28 publications

    1.5K citations

  7. Cornell University

    Ithaca, United States

    5 h-index

    6 publications

    459 citations

  8. Sorbonne Université

    Paris, France

    5 h-index

    30 publications

    2K citations

1–8 of 624

Venues

  1. Diabetes

    13 publications · 1.2K citations

    13

    h-index

  2. PubMed

    Repository · 12 publications · 313 citations

    11

    h-index

  3. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 6 publications · 373 citations

    6

    h-index

  4. Obesity

    5 publications · 323 citations

    5

    h-index

  5. 5

    h-index

1–5