Concepedia

Latency Reactivation

Latency Reactivation is a virological process in which a latent viral genome resumes active replication following a period of dormancy, distinguished from persistent or lytic infection modes by its transition from transcriptional quiescence to productive viral gene expression.

211

Publications

13.4K

Citations

1K

Authors

308

Institutions

Publications per year

2017–2026

63

Parents

Publications

211

The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy

Bharat Ramratnam, John E. Mittler, Linqi Zhang et al. · Nature Medicine · 2000 · 451 citations

, , +15

Transcriptional Activation by the Product of Open Reading Frame 50 of Kaposi’s Sarcoma-Associated Herpesvirus Is Required for Lytic Viral Reactivation in B Cells

David M. Lukac, Jessica R. Kirshner, Don Ganem · Journal of Virology · 1999 · 388 citations · Full text

, , +17

Generation of a doxycycline-inducible KSHV producer cell line of endothelial origin: Maintenance of tight latency with efficient reactivation upon induction

Jinjong Myoung, Don Ganem · Journal of Virological Methods · 2011 · 366 citations

, , +9

Latency, chromatin remodeling, and reactivation of human cytomegalovirus in the dendritic cells of healthy carriers

Matthew B. Reeves, Paul A. MacAry, Paul J. Lehner et al. · Proceedings of the National Academy of Sciences · 2005 · 359 citations · Full text

, , +17

HIV rebounds from latently infected cells, rather than from continuing low-level replication

Béda Joos, Marek Fischer, Herbert Kuster et al. · Proceedings of the National Academy of Sciences · 2008 · 304 citations · Full text

, , +17

1–5 of 211

Authors

1K

  1. CJ
    Clinton Jones

    University of Nebraska–Lincoln, United States

    17 publications · 851 citations

    15

    h-index

  2. SL
    Steven L. Wechsler

    Cedars-Sinai Medical Center, United States

    9 publications · 494 citations

    9

    h-index

  3. NS
    Nancy Sawtell

    Cincinnati Children's Hospital Medical Center, United States

    8 publications · 824 citations

    8

    h-index

  4. HG
    Homayon Ghiasi

    Cedars-Sinai Medical Center, United States

    8 publications · 416 citations

    8

    h-index

  5. DC
    David C. Bloom

    University of Florida, United States

    7 publications · 295 citations

    7

    h-index

1–5 of 1K

Institutions

308

  1. University of Nebraska–Lincoln

    Lincoln, United States

    14 h-index

    40 publications

    2.1K citations

  2. University of California, Irvine

    Irvine, United States

    10 h-index

    55 publications

    2.4K citations

  3. Cedars-Sinai Medical Center

    Los Angeles, United States

    10 h-index

    46 publications

    2.2K citations

  4. Emory University

    Atlanta, United States

    8 h-index

    16 publications

    1K citations

  5. University of Cambridge

    Cambridge, United Kingdom

    8 h-index

    40 publications

    3.3K citations

  6. University of Cincinnati

    Cincinnati, United States

    7 h-index

    13 publications

    1.7K citations

  7. Louisiana State University Health Sciences Center New Orleans

    New Orleans, United States

    7 h-index

    26 publications

    1.1K citations

  8. University of Florida

    Gainesville, United States

    7 h-index

    22 publications

    956 citations

1–8 of 308

Venues

  1. Journal of Virology

    JVI · 71 publications · 4.9K citations

    39

    h-index

  2. Journal of General Virology

    12 publications · 695 citations

    11

    h-index

  3. PLoS Pathogens

    8 publications · 552 citations

    8

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 1K citations

    7

    h-index

  5. PLoS ONE

    6 publications · 148 citations

    6

    h-index

1–5