Concepedia

Label-free Quantification

Label-Free Quantification is a computational method in proteomics informatics that belongs to the class of protein quantification techniques and is distinguished by its reliance on the direct comparison of peptide signal intensities across mass spectrometry runs without the use of isotopic or chemical labeling.

911

Publications

65.7K

Citations

4.9K

Authors

1.3K

Institutions

Publications per year

2017–2026

343

Variants

Label-free Quantitation

Parents

Children

Publications

911

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

Jürgen Cox, Marco Y. Hein, Christian A. Luber et al. · Molecular & Cellular Proteomics · 2014 · 5.5K citations · Full text

, , +16

Multiplexed Protein Quantitation in Saccharomyces cerevisiae Using Amine-reactive Isobaric Tagging Reagents

Philip L. Ross, Yulin Huang, Jason Marchese et al. · Molecular & Cellular Proteomics · 2004 · 4.4K citations · Full text

, , +12

Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics

Paul J. Boersema, Reinout Raijmakers, Simone Lemeer et al. · Nature Protocols · 2009 · 1.4K citations

, , +14

Comparison of Label-free Methods for Quantifying Human Proteins by Shotgun Proteomics

William M. Old, Karen Meyer-Arendt, Lauren D. Aveline-Wolf et al. · Molecular & Cellular Proteomics · 2005 · 1.2K citations · Full text

, , +16

MSstats: an R package for statistical analysis of quantitative mass spectrometry-based proteomic experiments

Meena Choi, Ching-Yun Chang, Timothy Clough et al. · Bioinformatics · 2014 · 1.2K citations

, , +17

1–5 of 911

Authors

4.9K

  1. OV
    Olga Vitek

    Purdue University West Lafayette, United States

    12 publications · 2.5K citations

    12

    h-index

  2. RA
    Ruedi Aebersold

    ETH Zurich, Switzerland

    12 publications · 2.5K citations

    11

    h-index

  3. AI
    Alexey I. Nesvizhskii

    University of Michigan, United States

    9 publications · 1.9K citations

    9

    h-index

  4. RS
    Richard Smith

    Pacific Northwest National Laboratory, United States

    9 publications · 898 citations

    9

    h-index

  5. MM
    Matthias Mann

    Max Planck Institute of Biochemistry, Germany

    9 publications · 7.1K citations

    9

    h-index

1–5 of 4.9K

Institutions

1.3K

  1. Centre National de la Recherche Scientifique

    Paris, France

    18 h-index

    115 publications

    9.2K citations

  2. University of Michigan

    Ann Arbor, United States

    18 h-index

    68 publications

    9.4K citations

  3. Chinese Academy of Sciences

    Beijing, China

    18 h-index

    108 publications

    8.4K citations

  4. ETH Zurich

    Zurich, Switzerland

    17 h-index

    72 publications

    11.2K citations

  5. University of Zurich

    Zurich, Switzerland

    15 h-index

    37 publications

    4.7K citations

  6. University of Cambridge

    Cambridge, United Kingdom

    15 h-index

    48 publications

    3K citations

  7. Max Planck Institute of Biochemistry

    Martinsried, Germany

    14 h-index

    42 publications

    39.1K citations

  8. University of Washington

    Seattle, United States

    14 h-index

    57 publications

    13.6K citations

1–8 of 1.3K

Venues

  1. Journal of Proteome Research

    JPR · 133 publications · 9.5K citations

    53

    h-index

  2. Molecular & Cellular Proteomics

    MCP · 68 publications · 17.4K citations

    49

    h-index

  3. Analytical Chemistry

    55 publications · 2.8K citations

    30

    h-index

  4. Journal of Proteomics

    47 publications · 2.4K citations

    30

    h-index

  5. PROTEOMICS

    54 publications · 3K citations

    29

    h-index

1–5