Concepedia

Keratin 16

Keratin 16 is a type I intermediate filament protein that, as a structural component of epithelial cells, distinguishes itself by its specific expression in hyperproliferative keratinocytes and its critical role in maintaining epidermal integrity, with mutations in its encoding gene (KRT16) being causally associated with Pachyonychia Congenita.

233

Publications

16.1K

Citations

1K

Authors

337

Institutions

Publications per year

2017–2026

23

Variants

Krt16

Parents

Publications

233

The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

Karl Münger, William C. Phelps, Vivien J. Bubb et al. · Journal of Virology · 1989 · 1.3K citations · Full text

, , +15

Correlation of specific keratins with different types of epithelial differentiation: Monoclonal antibody studies

Scheffer C.G. Tseng, Mikko Järvinen, William G. Nelson et al. · Cell · 1982 · 668 citations

, , +16

Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16.

Rudolph D. Paladini, Ken Takahashi, Nicola S. Bravo et al. · The Journal of Cell Biology · 1996 · 418 citations · Full text

, , +14

Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge

Yaping Liu, Stephen Lyle, Zaixin Yang et al. · Journal of Investigative Dermatology · 2003 · 386 citations

, , +10

Keratin 16 and keratin 17 mutations cause pachyonychia congenita

W.H. Irwin McLean, E.L. Rugg, Declan P. Lunny et al. · Nature Genetics · 1995 · 354 citations

, , +9

1–5 of 233

Authors

1K

  1. PA
    Pierre A. Coulombe

    Johns Hopkins University, United States

    22 publications · 2.4K citations

    21

    h-index

  2. EB
    E. Birgitte Lane

    University of Dundee, United Kingdom

    15 publications · 1.8K citations

    15

    h-index

  3. IM
    Irene M. Leigh

    Royal London Hospital, United Kingdom

    13 publications · 1.7K citations

    13

    h-index

  4. WI
    W.H. Irwin McLean

    University of Dundee, United Kingdom

    12 publications · 1.1K citations

    12

    h-index

  5. PV
    P.C.M. van de Kerkhof

    Radboud University Nijmegen, Netherlands

    10 publications · 371 citations

    10

    h-index

1–5 of 1K

Institutions

337

  1. Johns Hopkins Medicine

    Baltimore, United States

    22 h-index

    48 publications

    9.2K citations

  2. Johns Hopkins University

    Baltimore, United States

    22 h-index

    73 publications

    11.4K citations

  3. University of Dundee

    Dundee, United Kingdom

    17 h-index

    39 publications

    4.5K citations

  4. Radboud University Nijmegen

    Nijmegen, The Netherlands

    14 h-index

    49 publications

    1.8K citations

  5. Royal London Hospital

    London, United Kingdom

    13 h-index

    32 publications

    4K citations

  6. University of Michigan

    Ann Arbor, United States

    7 h-index

    25 publications

    1.4K citations

  7. Stanford University

    Stanford, United States

    6 h-index

    16 publications

    1.1K citations

  8. Queen Mary University of London

    London, United Kingdom

    6 h-index

    15 publications

    704 citations

1–8 of 337

Venues

  1. Journal of Investigative Dermatology

    JID · 25 publications · 2.2K citations

    21

    h-index

  2. British Journal of Dermatology

    13 publications · 735 citations

    12

    h-index

  3. PubMed

    Repository · 11 publications · 502 citations

    10

    h-index

  4. Virology

    10 publications · 610 citations

    10

    h-index

  5. Archives of Dermatological Research

    7 publications · 210 citations

    7

    h-index

1–5