Concepedia

Isotype Function

Isotype Function is a biochemical property that categorizes immunoglobulins into distinct classes based on conserved structural and functional characteristics of their heavy chain constant regions, thereby determining effector functions and biological roles in the immune response.

298

Publications

18.2K

Citations

1.3K

Authors

429

Institutions

Publications per year

2017–2026

19

Parents

Publications

298

IFN- <i>gamma</i> regulates the isotypes of Ig secreted during in vivo humoral immune responses.

Fred D. Finkelman, Ildy M. Katona, Tim R. Mosmann et al. · The Journal of Immunology · 1988 · 724 citations · Full text

, , +14

Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes.

Robert L. Coffman, Deborah A. Lebman, B Shrader · The Journal of Experimental Medicine · 1989 · 580 citations · Full text

, , +16

Humoral immune responses in CD40 ligand-deficient mice.

Blair R. Renshaw, William C. Fanslow, Richard J. Armitage et al. · The Journal of Experimental Medicine · 1994 · 539 citations · Full text

, , +16

TACI and BAFF-R mediate isotype switching in B cells

Emanuela Castigli, Stephen A. Wilson, Sumi Scott et al. · The Journal of Experimental Medicine · 2005 · 535 citations · Full text

, , +12

Proinflammatory T helper type 17 cells are effective B-cell helpers

Meike Mitsdoerffer, Youjin Lee, Anneli Jäger et al. · Proceedings of the National Academy of Sciences · 2010 · 534 citations · Full text

, , +17

1–5 of 298

Authors

1.3K

  1. JM
    Judy M. Teale

    The University of Texas at San Antonio Health Science Center, United States

    6 publications · 157 citations

    6

    h-index

  2. FK
    Freda K. Stevenson

    Southampton General Hospital, United Kingdom

    4 publications · 174 citations

    4

    h-index

  3. KL
    Katherine L. Knight

    Loyola University Chicago, United States

    4 publications · 124 citations

    4

    h-index

  4. HL
    Hans Loibner

    Apeiron Biologics (Austria), Austria

    3 publications · 95 citations

    3

    h-index

  5. SL
    Sherie L. Morrison

    University of California, Los Angeles, United States

    3 publications · 125 citations

    3

    h-index

1–5 of 1.3K

Institutions

429

  1. Inserm

    Paris, France

    9 h-index

    30 publications

    2.4K citations

  2. Harvard University

    Cambridge, United States

    8 h-index

    38 publications

    6.6K citations

  3. National Institutes of Health

    Bethesda, United States

    7 h-index

    15 publications

    382 citations

  4. Institut Pasteur

    Paris, France

    7 h-index

    21 publications

    1.5K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    14 publications

    1.2K citations

  6. Albert Einstein College of Medicine

    Bronx, United States

    6 h-index

    18 publications

    1.2K citations

  7. University of Birmingham

    Birmingham, United Kingdom

    5 h-index

    13 publications

    526 citations

  8. Johns Hopkins University

    Baltimore, United States

    5 h-index

    11 publications

    944 citations

1–8 of 429

Venues

  1. The Journal of Immunology

    JI · 51 publications · 3.2K citations

    30

    h-index

  2. The Journal of Experimental Medicine

    20 publications · 3.3K citations

    18

    h-index

  3. European Journal of Immunology

    EJI · 20 publications · 1.2K citations

    17

    h-index

  4. Molecular Immunology

    15 publications · 399 citations

    13

    h-index

  5. PubMed

    Repository · 19 publications · 553 citations

    13

    h-index

1–5