Concepedia

Isoform-specific Protein Profiling

Isoform-Specific Protein Profiling is an analytical approach within activity-based protein profiling that selectively targets and characterizes the functional states of individual protein isoforms, distinguished by their unique post-translational modifications, substrate specificities, or subcellular localizations, to enable precise mapping of isoform-resolved enzymatic activities in complex biological systems.

49

Publications

2.3K

Citations

282

Authors

112

Institutions

Publications per year

2017–2026

9

Parents

Publications

49

Purification, structural characterization, cloning and immunocytochemical localization of chemoreception proteins from <i>Schistocerca gregaria</i>

Sergio Angeli, Francesca Ceron, Andrea Scaloni et al. · European Journal of Biochemistry · 1999 · 296 citations · Full text

, , +13

Combining LOPIT with differential ultracentrifugation for high-resolution spatial proteomics

Aikaterini Geladaki, Nina Kočevar Britovšek, Lisa M. Breckels et al. · Nature Communications · 2019 · 231 citations · Full text

, , +17

Protein isoform-specific validation defines multiple chloride intracellular channel and tropomyosin isoforms as serological biomarkers of ovarian cancer

Hsin‐Yao Tang, Lynn A. Beer, János L. Tanyi et al. · Journal of Proteomics · 2013 · 95 citations · Full text

, , +17

An Integrated Top-Down and Bottom-Up Strategy for Broadly Characterizing Protein Isoforms and Modifications

Si Wu, Natacha Lourette, Nikola Tolić et al. · Journal of Proteome Research · 2009 · 90 citations · Full text

, , +17

Are genuine changes in protein expression being overlooked? Reassessing Western blotting

Janelle P. Mollica, Jonathan S. Oakhill, Graham D. Lamb et al. · Analytical Biochemistry · 2009 · 82 citations

, , +13

1–5 of 49

Authors

282

  1. NT
    Nikola Tolić

    Pacific Northwest National Laboratory, United States

    2 publications · 100 citations

    2

    h-index

  2. SW
    Si Wu

    Pacific Northwest National Laboratory, United States

    2 publications · 100 citations

    2

    h-index

  3. ER
    Errol Robinson

    Pacific Northwest National Laboratory, United States

    2 publications · 100 citations

    2

    h-index

  4. LP
    Ljiljana Paša‐Tolić

    Pacific Northwest National Laboratory, United States

    2 publications · 100 citations

    2

    h-index

  5. HY
    Hyesook Yoon

    Mayo Clinic in Arizona, United States

    1 publications · 51 citations

    1

    h-index

1–5 of 282

Institutions

112

  1. Karolinska Institutet

    Stockholm, Sweden

    2 h-index

    3 publications

    54 citations

  2. Pacific Northwest National Laboratory

    Richland, United States

    2 h-index

    13 publications

    770 citations

  3. Uppsala University

    Uppsala, Sweden

    2 h-index

    3 publications

    82 citations

  4. Florida State University

    Tallahassee, United States

    2 h-index

    5 publications

    175 citations

  5. National Research Council

    Rome, Italy

    1 h-index

    2 publications

    592 citations

  6. New York University

    New York, United States

    1 h-index

    2 publications

    42 citations

  7. XOMA (United States)

    Berkeley, United States

    1 h-index

    2 publications

    90 citations

  8. Charlottesville Medical Research

    Charlottesville, United States

    1 h-index

    3 publications

    147 citations

1–8 of 112

Venues

  1. Journal of Proteome Research

    JPR · 5 publications · 275 citations

    5

    h-index

  2. Molecular & Cellular Proteomics

    MCP · 3 publications · 78 citations

    3

    h-index

  3. PROTEOMICS - CLINICAL APPLICATIONS

    2 publications · 89 citations

    2

    h-index

  4. Methods in molecular biology

    Book series · 2 publications · 32 citations

    2

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 2 publications · 80 citations

    2

    h-index

1–5