Concepedia

Isoform Switching

Isoform Switching is a biological phenomenon in which the relative expression levels of different transcript isoforms produced from the same gene change significantly across conditions, cell types, or developmental stages, leading to a shift in the dominant isoform.

179

Publications

29.2K

Citations

1.2K

Authors

455

Institutions

Publications per year

2017–2026

64

Parents

Publications

179

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

Cole Trapnell, Brian A. Williams, Geo Pertea et al. · Nature Biotechnology · 2010 · 16.5K citations

, , +16

CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

Rhonda L. Brown, Lauren M. Reinke, Marin S. Damerow et al. · Journal of Clinical Investigation · 2011 · 649 citations · Full text

, , +17

All Members of the MHC Multigene Family Respond to Thyroid Hormone in a Highly Tissue-Specific Manner

Seigo Izumo, Bernardo Nadal‐Ginard, Vijak Mahdavi · Science · 1986 · 627 citations

, , +12

TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II

Jo El J. Schultz, Sandra A. Witt, Betty J. Glascock et al. · Journal of Clinical Investigation · 2002 · 428 citations · Full text

, , +13

Distribution and Prevalence of Hyperpolarization-Activated Cation Channel (HCN) mRNA Expression in Cardiac Tissues

Wenmei Shi, Randy S. Wymore, Han‐Gang Yu et al. · Circulation Research · 1999 · 385 citations · Full text

, , +17

1–5 of 179

Authors

1.2K

  1. KV
    Kristoffer Vitting‐Seerup

    University of Copenhagen, Denmark

    3 publications · 661 citations

    4

    h-index

  2. SA
    Sandra A. Witt

    Cincinnati Children's Hospital Medical Center, United States

    3 publications · 805 citations

    3

    h-index

  3. BJ
    Betty J. Glascock

    Cincinnati Children's Hospital Medical Center, United States

    3 publications · 805 citations

    3

    h-index

  4. AS
    Albin Sandelin

    University of Copenhagen, Denmark

    3 publications · 661 citations

    3

    h-index

  5. JE
    Jo El J. Schultz

    University of Cincinnati Medical Center, United States

    3 publications · 805 citations

    3

    h-index

1–5 of 1.2K

Institutions

455

  1. The University of Texas MD Anderson Cancer Center

    Houston, United States

    5 h-index

    16 publications

    1.1K citations

  2. Cincinnati Children's Hospital Medical Center

    Cincinnati, United States

    5 h-index

    19 publications

    3.4K citations

  3. University of California San Diego

    San Diego, United States

    5 h-index

    45 publications

    3.1K citations

  4. Inserm

    Paris, France

    5 h-index

    24 publications

    1.1K citations

  5. University of Iowa

    Iowa City, United States

    4 h-index

    7 publications

    307 citations

  6. Northwestern University

    Evanston, United States

    4 h-index

    10 publications

    1.9K citations

  7. Laboratory of Molecular Genetics

    Poznań, Poland

    4 h-index

    17 publications

    2.6K citations

  8. Johns Hopkins University

    Baltimore, United States

    4 h-index

    17 publications

    959 citations

1–8 of 455

Venues

  1. Journal of Biological Chemistry

    JBC · 13 publications · 826 citations

    13

    h-index

  2. Journal of Clinical Investigation

    JCI · 6 publications · 1.9K citations

    6

    h-index

  3. Scientific Reports

    6 publications · 372 citations

    6

    h-index

  4. PLoS ONE

    6 publications · 128 citations

    6

    h-index

  5. American Journal of Physiology-Cell Physiology

    5 publications · 245 citations

    5

    h-index

1–5