Seigo Izumo

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

Elisabeth M. Zeisberg, Oleg Tarnavski, Michael Zeisberg et al. · Nature Medicine · 2007 · 2.2K citations

Fibrosis, Physiology, Endothelial-to-mesenchymal Transition Contributes +6

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.

Junichi Sadoshima, Seigo Izumo · Circulation Research · 1993 · 1.4K citations · Full text

Cardiac Muscle, Heart Failure, At1 Receptor Subtype +16

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload.

Seigo Izumo, B Nadal-Ginard, Vijak Mahdavi · Proceedings of the National Academy of Sciences · 1988 · 868 citations · Full text

Skeletal Muscle Cells, Cardiac Muscle, Skeletal Muscle Type +19

Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism.

Junichi Sadoshima, Seigo Izumo · The EMBO Journal · 1993 · 667 citations

Mechanobiology, Cardiac Muscle, Muscle Physiology +13

All Members of the MHC Multigene Family Respond to Thyroid Hormone in a Highly Tissue-Specific Manner

Seigo Izumo, Bernardo Nadal‐Ginard, Vijak Mahdavi · Science · 1986 · 627 citations

Genetics, Immunology, Molecular Genetics +20