Concepedia

Irf6 Variants

IRF6 Variants is a genetic construct denoting specific allelic alterations in the Interferon Regulatory Factor 6 gene that are associated with an increased susceptibility to non-syndromic cleft lip, distinguishing it from other craniofacial anomaly-related genetic variants by its locus-specific pathogenicity and population-level inheritance patterns.

94

Publications

4.9K

Citations

702

Authors

257

Institutions

Publications per year

2017–2026

17

Parents

Publications

94

Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes

Shinji Kondo, Brian C. Schutte, Rebecca J. Richardson et al. · Nature Genetics · 2002 · 901 citations · Full text

, , +5

Interferon Regulatory Factor 6 ( <i>IRF6</i> ) Gene Variants and the Risk of Isolated Cleft Lip or Palate

Theresa M. Zucchero, Margaret E. Cooper, Brion S. Maher et al. · New England Journal of Medicine · 2004 · 583 citations · Full text

, , +15

Buccal cells DNA extraction to obtain high quality human genomic DNA suitable for polymorphism genotyping by PCR-RFLP and Real-Time PCR

Érika Calvano Küchler, Patrícia Nivoloni Tannure, Priscila Falagan-Lotsch et al. · Journal of Applied Oral Science · 2012 · 164 citations · Full text

, , +13

Strong Evidence of Linkage Disequilibrium between Polymorphisms at the IRF6 Locus and Nonsyndromic Cleft Lip With or Without Cleft Palate, in an Italian Population

Luca Scapoli, Annalisa Palmieri, Marcella Martinelli et al. · The American Journal of Human Genetics · 2004 · 162 citations · Full text

, , +17

Variation in IRF6 contributes to nonsyndromic cleft lip and palate

Susan H. Blanton, Amy Cortez, Samuel Stal et al. · American Journal of Medical Genetics Part A · 2005 · 136 citations · Full text

, , +17

1–5 of 94

Authors

702

  1. JC
    Jeffrey C. Murray

    University of Iowa, United States

    14 publications · 2.2K citations

    14

    h-index

  2. BC
    Brian C. Schutte

    University of Iowa, United States

    11 publications · 1.9K citations

    11

    h-index

  3. ML
    Mary L. Marazita

    University of Pittsburgh, United States

    6 publications · 813 citations

    6

    h-index

  4. AR
    Alexandre R. Vieira

    University of Pittsburgh, United States

    5 publications · 794 citations

    5

    h-index

  5. AC
    Andrew C. Lidral

    University of Iowa, United States

    5 publications · 1.8K citations

    5

    h-index

1–5 of 702

Institutions

257

  1. University of Iowa

    Iowa City, United States

    16 h-index

    63 publications

    15.5K citations

  2. University of Pittsburgh

    Pittsburgh, United States

    11 h-index

    26 publications

    3.4K citations

  3. Michigan State University

    East Lansing, United States

    8 h-index

    15 publications

    611 citations

  4. Universidade de São Paulo

    São Paulo, Brazil

    6 h-index

    32 publications

    2.4K citations

  5. The University of Texas Health Science Center at Houston

    Houston, United States

    5 h-index

    18 publications

    667 citations

  6. Universidade Federal do Rio de Janeiro

    Rio de Janeiro, Brazil

    5 h-index

    6 publications

    1.1K citations

  7. Sichuan University

    Chengdu, China

    5 h-index

    34 publications

    1.1K citations

  8. University of Bonn

    Bonn, Germany

    4 h-index

    34 publications

    1.7K citations

1–8 of 257

Venues

  1. American Journal of Medical Genetics Part A

    12 publications · 552 citations

    12

    h-index

  2. Journal of Dental Research

    JDR · 6 publications · 155 citations

    6

    h-index

  3. International Journal of Molecular Medicine

    5 publications · 94 citations

    5

    h-index

  4. The Cleft Palate-Craniofacial Journal

    4 publications · 101 citations

    4

    h-index

  5. PLoS ONE

    4 publications · 208 citations

    4

    h-index

1–5