Concepedia

Interstrand Crosslink Recognition

Interstrand Crosslink Recognition is the molecular process by which specialized DNA repair proteins identify and bind to covalent linkages between complementary strands of DNA, distinguishing it from other DNA lesion recognition mechanisms by its specificity for duplex-intertwined adducts that block strand separation.

58

Publications

2.5K

Citations

205

Authors

77

Institutions

Publications per year

2017–2026

3

Variants

Icl Recognition

Parents

Publications

58

The colibactin warhead crosslinks DNA

Maria I. Vizcaino, Jason M. Crawford · Nature Chemistry · 2015 · 245 citations · Full text

, , +4

Selective recognition of a cisplatin-DNA adduct by human mismatch repair proteins

Masami Yamada · Nucleic Acids Research · 1997 · 166 citations · Full text

, , +17

UHRF1 Contributes to DNA Damage Repair as a Lesion Recognition Factor and Nuclease Scaffold

Yanyan Tian, Manikandan Paramasivam, Gargi Ghosal et al. · Cell Reports · 2015 · 99 citations · Full text

, , +17

Photoaffinity Labeling Reveals Nuclear Proteins That Uniquely Recognize Cisplatin−DNA Interstrand Cross-Links

Guangyu Zhu, Stephen J. Lippard · Biochemistry · 2009 · 82 citations · Full text

, , +16

Effects of Spectator Ligands on the Specific Recognition of Intrastrand Platinum-DNA Cross-links by High Mobility Group Box and TATA-binding Proteins

Min Wei, Seth M. Cohen, Adam P. Silverman et al. · Journal of Biological Chemistry · 2001 · 79 citations · Full text

, , +17

1–5 of 58

Authors

205

  1. AM
    Anne M. Noronha

    Concordia University, Canada

    5 publications · 128 citations

    5

    h-index

  2. CJ
    Christopher J. Wilds

    Concordia University, Canada

    4 publications · 115 citations

    4

    h-index

  3. PB
    Paul B. Hopkins

    University of Washington, United States

    4 publications · 122 citations

    4

    h-index

  4. SJ
    Stephen J. Lippard

    Massachusetts Institute of Technology, United States

    3 publications · 205 citations

    3

    h-index

  5. DM
    David M. Noll

    Johns Hopkins University, United States

    2 publications · 33 citations

    2

    h-index

1–5 of 205

Institutions

77

  1. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    12 publications

    439 citations

  2. Concordia University

    Montreal, Canada

    4 h-index

    20 publications

    598 citations

  3. Johns Hopkins University

    Baltimore, United States

    4 h-index

    22 publications

    587 citations

  4. National Institutes of Health

    Bethesda, United States

    3 h-index

    10 publications

    638 citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    10 publications

    656 citations

  6. Centre de Biophysique Moléculaire

    Orléans, France

    3 h-index

    8 publications

    486 citations

  7. Institut Curie

    Paris, France

    2 h-index

    2 publications

    52 citations

  8. Fox Chase Cancer Center

    Philadelphia, United States

    2 h-index

    4 publications

    134 citations

1–8 of 77

Venues

  1. Biochemistry

    9 publications · 423 citations

    9

    h-index

  2. Nucleic Acids Research

    8 publications · 541 citations

    8

    h-index

  3. Journal of the American Chemical Society

    JACS · 4 publications · 167 citations

    4

    h-index

  4. Organic & Biomolecular Chemistry

    3 publications · 52 citations

    3

    h-index

  5. PubMed

    Repository · 3 publications · 105 citations

    3

    h-index

1–5