Concepedia

Interoccasion Variability Modeling

Interoccasion Variability Modeling is a statistical modeling approach in population pharmacokinetics that characterizes within-subject fluctuations in drug exposure across multiple dosing occasions by distinguishing temporal variations from other sources of biological and analytical noise.

27

Publications

1.5K

Citations

148

Authors

77

Institutions

Publications per year

2017–2026

5

Variants

Inter-occasion Variability Modeling

Parents

Publications

27

The importance of modeling interoccasion variability in population pharmacokinetic analyses

Mats O. Karlsson, Lewis B. Sheiner · Journal of Pharmacokinetics and Biopharmaceutics · 1993 · 484 citations

, , +14

Further Developments of the Fisher Information Matrix in Nonlinear Mixed Effects Models with Evaluation in Population Pharmacokinetics

Sylvie Retout, France Mentré · Journal of Biopharmaceutical Statistics · 2003 · 108 citations

, , +17

A population pharmacokinetic model to predict the individual starting dose of tacrolimus in adult renal transplant recipients

Louise M. Andrews, Dennis A. Hesselink, Ron H. N. van Schaik et al. · British Journal of Clinical Pharmacology · 2018 · 102 citations · Full text

, , +17

Population Pharmacokinetics of Eltrombopag in Healthy Subjects and Patients With Chronic Idiopathic Thrombocytopenic Purpura

Ekaterina Gibiansky, Jianping Zhang, Daphne Williams et al. · The Journal of Clinical Pharmacology · 2010 · 86 citations

, , +17

Model Describing the Relationship Between Pharmacokinetics and Hematologic Toxicity of the Epirubicin-Docetaxel Regimen in Breast Cancer Patients

Marie Sandström, Henrik Lindman, Peter Nygren et al. · Journal of Clinical Oncology · 2004 · 75 citations · Full text

, , +17

1–5 of 27

Authors

148

  1. MO
    Mats O. Karlsson

    Uppsala University, Sweden

    5 publications · 676 citations

    5

    h-index

  2. AD
    Alwin D. R. Huitema

    The Netherlands Cancer Institute, Netherlands

    2 publications · 37 citations

    2

    h-index

  3. DO
    Danièle Ouellet

    GlaxoSmithKline (United States), United States

    2 publications · 98 citations

    2

    h-index

  4. NL
    Núria Lloberas

    Bellvitge University Hospital, Spain

    2 publications · 141 citations

    2

    h-index

  5. SA
    Stella Apostolidi

    Hippocration General Hospital, Greece

    1 publications · 13 citations

    1

    h-index

1–5 of 148

Institutions

77

  1. Uppsala University

    Uppsala, Sweden

    6 h-index

    19 publications

    986 citations

  2. Research Triangle Park Foundation

    Durham, United States

    2 h-index

    3 publications

    221 citations

  3. Slotervaartziekenhuis

    Amsterdam, Netherlands

    2 h-index

    8 publications

    148 citations

  4. Bellvitge University Hospital

    Barcelona, Spain

    2 h-index

    6 publications

    297 citations

  5. University of California, San Francisco

    San Francisco, United States

    2 h-index

    4 publications

    1K citations

  6. Utrecht University

    Utrecht, The Netherlands

    2 h-index

    3 publications

    62 citations

  7. UCLouvain

    Louvain-la-Neuve, Belgium

    1 h-index

    1 publications

    102 citations

  8. Royal Brisbane and Women's Hospital

    Brisbane, Australia

    1 h-index

    1 publications

    15 citations

1–8 of 77

Venues

  1. British Journal of Clinical Pharmacology

    BJCP · 6 publications · 290 citations

    6

    h-index

  2. Therapeutic Drug Monitoring

    4 publications · 104 citations

    4

    h-index

  3. 2

    h-index

  4. The Journal of Clinical Pharmacology

    2 publications · 128 citations

    2

    h-index

  5. Haemophilia

    1 publications · 15 citations

    1

    h-index

1–5