Concepedia

Integrative Structural Determination

Integrative Structural Determination is a computational and experimental methodology in macromolecular structure determination that synthesizes diverse, often heterogeneous, structural data types through unified modeling frameworks to generate comprehensive, multi-scale three-dimensional models of complex biological macromolecules and assemblies.

28

Publications

2.5K

Citations

211

Authors

108

Institutions

Publications per year

2017–2026

22

Parents

Publications

28

Putting the Pieces Together: Integrative Modeling Platform Software for Structure Determination of Macromolecular Assemblies

Daniel Russel, Keren Lasker, Ben Webb et al. · PLoS Biology · 2012 · 547 citations · Full text

, , +17

In-cell architecture of an actively transcribing-translating expressome

Francis J. O’Reilly, Liang Xue, Andrea Graziadei et al. · Science · 2020 · 294 citations · Full text

, , +14

2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update

Jill Trewhella, Anthony P. Duff, Dominique Durand et al. · Acta Crystallographica Section D Structural Biology · 2017 · 287 citations · Full text

, , +16

Determining protein structures by combining semireliable data with atomistic physical models by Bayesian inference

Justin L. MacCallum, Alberto Pérez, Ken A. Dill · Proceedings of the National Academy of Sciences · 2015 · 184 citations · Full text

, , +16

Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease

Gabriella T. Heller, Francesco A. Aprile, Thomas C. T. Michaels et al. · Science Advances · 2020 · 181 citations · Full text

, , +16

1–5 of 28

Authors

211

  1. AŠ
    Andrej Šali

    University of California, San Francisco, United States

    8 publications · 1.3K citations

    8

    h-index

  2. DS
    Dina Schneidman‐Duhovny

    Hebrew University of Jerusalem, Israel

    4 publications · 971 citations

    4

    h-index

  3. JR
    Juri Rappsilber

    Wellcome Centre for Cell Biology, United Kingdom

    3 publications · 348 citations

    3

    h-index

  4. JW
    John Westbrook

    Rutgers, The State University of New Jersey, United States

    3 publications · 428 citations

    3

    h-index

  5. AG
    Andrea Graziadei

    Technische Universität Berlin, Germany

    3 publications · 375 citations

    3

    h-index

1–5 of 211

Institutions

108

  1. QB3

    San Francisco, United States

    9 h-index

    39 publications

    6K citations

  2. University of California, San Francisco

    San Francisco, United States

    7 h-index

    35 publications

    5.7K citations

  3. Rutgers, The State University of New Jersey

    New Brunswick, United States

    4 h-index

    12 publications

    1.1K citations

  4. European Molecular Biology Laboratory

    Hamburg, Germany

    4 h-index

    11 publications

    1.2K citations

  5. University of Edinburgh

    Edinburgh, United Kingdom

    3 h-index

    3 publications

    348 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    4 publications

    506 citations

  7. Wellcome Centre for Cell Biology

    Edinburgh, United Kingdom

    3 h-index

    3 publications

    348 citations

  8. University of Göttingen

    Göttingen, Germany

    3 h-index

    6 publications

    984 citations

1–8 of 108

Venues

  1. Protein Science

    PS · 3 publications · 96 citations

    3

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 261 citations

    3

    h-index

  3. Bioinformatics

    2 publications · 169 citations

    2

    h-index

  4. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 53 citations

    2

    h-index

  5. Nature Communications

    2 publications · 130 citations

    2

    h-index

1–5