Thomas C. T. Michaels

Molecular mechanisms of protein aggregation from global fitting of kinetic models

Georg Meisl, Julius B. Kirkegaard, Paolo Arosio et al. · Nature Protocols · 2016 · 759 citations

Protein Chemistry, Kinetic Models, Global Fitting +13

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

Céline Galvagnion, Alexander K. Buell, Georg Meisl et al. · Nature Chemical Biology · 2015 · 663 citations · Full text

Proteinlipid Interaction, Neurodegenerative Diseases, Medicine +7

Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide

Thomas C. T. Michaels, Anđela Šarić, Samo Curk et al. · Nature Chemistry · 2020 · 334 citations · Full text

Neurodegenerative Diseases, Oligomer Populations, Alzheimer's Disease +12

Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation

Paolo Arosio, Thomas C. T. Michaels, Sara Linse et al. · Nature Communications · 2016 · 263 citations · Full text

Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes

Johnny Habchi, Sean Chia, Céline Galvagnion et al. · Nature Chemistry · 2018 · 246 citations · Full text

Proteinlipid Interaction, Biochemistry, Protein Misfolding +7