Concepedia

Concept

innate immune memory

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80

Publications

7.5K

Citations

479

Authors

201

Institutions

About

Innate immune memory is a concept within immunology describing the capacity of innate immune cells to develop long-lasting functional alterations following initial stimulation, leading to modified responses upon subsequent encounters with the same or unrelated stimuli. This field of research investigates the molecular, epigenetic, and metabolic mechanisms underpinning this non-specific form of immunological memory. Key characteristics include cellular reprogramming resulting in heightened or sometimes suppressed inflammatory and antimicrobial effector functions. Its significance lies in contributing to enhanced host defense, influencing adaptive immunity, and offering potential avenues for novel therapeutic and prophylactic interventions.

Top Authors

Rankings shown are based on concept H-Index.

MG

Radboud University Nijmegen

LA

Radboud University Nijmegen

BG

Centre National de la Recherche Scientifique

DB

National Research Council

PI

National Research Council

Top Institutions

Rankings shown are based on concept H-Index.

Radboud University Nijmegen

Nijmegen, The Netherlands

Radboud University Medical Center

Nijmegen, The Netherlands

Université de Montpellier

Montpellier, France

University of Bonn

Bonn, Germany

Yale University

New Haven, United States

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