Initiator Element Function is a cis-regulatory DNA sequence element that serves as a core promoter component by directing the accurate initiation of transcription through the recruitment and positioning of the RNA polymerase II machinery at the transcription start site.
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The “initiator” as a transcription control element
Stephen T. Smale, David Baltimore · Cell · 1989 · 1.6K citations
DNA sequence requirements for transcriptional initiator activity in mammalian cells.
Ramin Javahery, A Khachi, K M Lo et al. · Molecular and Cellular Biology · 1994 · 341 citations
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