Concepedia

Transcription Initiation

Transcription Initiation is the molecular process whereby RNA polymerase and associated transcription factors assemble at a gene's promoter region to form a transcription preinitiation complex, thereby marking the beginning of RNA synthesis in gene expression.

4.9K

Publications

390.9K

Citations

13.4K

Authors

2K

Institutions

Publications per year

2017–2026

432

Parents

Children

Publications

4.9K

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

John David Dignam, Russell M. Lebovitz, R G Roeder · Nucleic Acids Research · 1983 · 11.6K citations · Full text

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Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

Leighton J. Core, Joshua J. Waterfall, John T. Lis · Science · 2008 · 2.1K citations · Full text

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A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells

Matthew G. Guenther, Stuart S. Levine, Laurie A. Boyer et al. · Cell · 2007 · 2K citations · Full text

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The “initiator” as a transcription control element

Stephen T. Smale, David Baltimore · Cell · 1989 · 1.6K citations

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Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

Steven L. McKnight, Robert C. Kingsbury · Science · 1982 · 1.4K citations

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1–5 of 4.9K

Authors

13.4K

  1. RG
    Robert G. Roeder

    Rockefeller University, United States

    75 publications · 11K citations

    51

    h-index

  2. PC
    Patrick Cramer

    Max Planck Institute for Biophysical Chemistry, Germany

    39 publications · 6.7K citations

    32

    h-index

  3. RD
    Roger D. Kornberg

    Stanford University, United States

    37 publications · 6K citations

    32

    h-index

  4. RH
    Richard H. Ebright

    Rutgers, The State University of New Jersey, United States

    34 publications · 5.1K citations

    30

    h-index

  5. DR
    Danny Reinberg

    Howard Hughes Medical Institute, United States

    30 publications · 5.4K citations

    28

    h-index

1–5 of 13.4K

Institutions

2K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    89 h-index

    184 publications

    25.4K citations

  2. Harvard University

    Cambridge, United States

    77 h-index

    163 publications

    24.4K citations

  3. Rockefeller University

    New York, United States

    73 h-index

    133 publications

    17.4K citations

  4. University of Wisconsin–Madison

    Madison, United States

    68 h-index

    154 publications

    12.8K citations

  5. Stanford University

    Stanford, United States

    63 h-index

    123 publications

    16.8K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    63 h-index

    178 publications

    14.7K citations

  7. University of California, Berkeley

    Berkeley, United States

    57 h-index

    91 publications

    10.2K citations

  8. National Institutes of Health

    Bethesda, United States

    53 h-index

    126 publications

    10.5K citations

1–8 of 2K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 419 publications · 41.9K citations

    110

    h-index

  2. Cell

    129 publications · 33K citations

    98

    h-index

  3. Journal of Biological Chemistry

    JBC · 600 publications · 37.9K citations

    97

    h-index

  4. Molecular and Cellular Biology

    MCB · 492 publications · 30.8K citations

    87

    h-index

  5. Nature

    98 publications · 23K citations

    75

    h-index

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