Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome

Daniel G. Gibson, John I. Glass, Carole Lartigue, +21

Science

EngineeringGeneticsBacteriologyMolecular BiologySynthetic Circuit +20

Creating Bacterial Strains from Genomes That Have Been Cloned and Engineered in Yeast

Carole Lartigue, Sanjay Vashee, Mikkel A. Algire, +14

Science

EngineeringGeneticsMolecular BiologySynthetic CircuitYeast +14

Sequence-independent DNA binding and replication initiation by the human origin recognition complex

Sanjay Vashee, Christin Cvetic, Wenyan Lü, +3

Genes & Development

BiologyChromatinSequence MotifDna SequencingHuman Origin Sequences +12

Cloning whole bacterial genomes in yeast

Gwynedd A. Benders, Vladimir N. Noskov, Evgeniya A. Denisova, +15

Nucleic Acids Research

EngineeringGeneticsWhole GenomesSynthetic BiologyGenetic Engineering +13

Assembly of the Human Origin Recognition Complex

Sanjay Vashee, Pamela Simancek, M D Challberg, +1

Journal of Biological Chemistry

Maternal carriage of Prevotella during pregnancy associates with protection against food allergy in the offspring

Peter Vuillermin, Martin O’Hely, Fiona Collier, +21

Nature Communications

Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses

Benjamín L. Sievers, Saborni Chakraborty, Yong Xue, +19

Science Translational Medicine

VaccinationSpike ProteinVaccine DevelopmentMrna Vaccine ResponsesVaccine Target +13

MIB–MIP is a mycoplasma system that captures and cleaves immunoglobulin G

Yonathan Arfi, Carmelo Di Primo, Aline Le Roy, +7

Proceedings of the National Academy of Sciences

ImmunodeficienciesImmunologyPathologyAntigen ProcessingImmune System +14

How do “Zn2 cys6” proteins distinguish between similar upstream activation sites? Comparison of the DNA-binding specificity of the GAL4 protein in vitro and in vivo.

Sanjay Vashee, Hao Xu, S. A. Johnston, +1

Journal of Biological Chemistry

Genome-wide engineering of an infectious clone of herpes simplex virus type 1 using synthetic genomics assembly methods

Lauren M. Oldfield, Peter Grzesik, Alexander A. Voorhies, +10

Proceedings of the National Academy of Sciences