Concepedia

Inhibitor Dosing Optimization

Inhibitor Dosing Optimization is a methodological framework within chemical inhibition science that systematically determines the minimal effective concentration of an inhibitor to achieve desired reaction suppression while minimizing excess reagent use, cost, and potential side effects.

11

Publications

365

Citations

95

Authors

39

Institutions

Publications per year

2017–2026

0

Parents

Publications

11

Sub‐optimal proton pump inhibitor dosing is prevalent in patients with poorly controlled gastro‐oesophageal reflux disease

Naresh T. Gunaratnam, T. P. JESSUP, John M. Inadomi et al. · Alimentary Pharmacology & Therapeutics · 2006 · 142 citations · Full text

, , +13

Discovery of a Potent Class I Selective Ketone Histone Deacetylase Inhibitor with Antitumor Activity in Vivo and Optimized Pharmacokinetic Properties

Olaf Kinzel, Laura Llauger-Bufi, Giovanna Pescatore et al. · Journal of Medicinal Chemistry · 2009 · 45 citations · Full text

, , +14

Optimization of irinotecan chronotherapy with P-glycoprotein inhibition

Elisabeth Filipski, Elodie Berland, Narin Öztürk et al. · Toxicology and Applied Pharmacology · 2014 · 39 citations

, , +11

Comparative study and optimisation of the administration mode of three proton pump inhibitors by nasogastric tube

D. Messaouik, Valérie Sautou, S. Bagel-Boithias et al. · International Journal of Pharmaceutics · 2005 · 29 citations

, , +12

Definition of the effective dose of the converting-enzyme inhibitor benazepril

John J. Whalen · American Heart Journal · 1989 · 22 citations

, , +11

1–5 of 11

Authors

95

  1. AO
    Alper Okyar

    Istanbul University, Türkiye

    1 publications · 39 citations

    1

    h-index

  2. MM
    Morten Mau‐Sørensen

    Rigshospitalet, Denmark

    1 publications · 15 citations

    1

    h-index

  3. XY
    Xu Yang

    Xiangtan University, China

    1 publications · 13 citations

    1

    h-index

  4. WC
    Wilson Caulfield

    Discovery Laboratories (United States), United States

    1 publications · 11 citations

    1

    h-index

  5. HM
    Harry Montgomerie

    Equinor (Norway), Norway

    1 publications · 13 citations

    1

    h-index

1–5 of 95

Institutions

39

  1. Merck Serono Ltd. (United Kingdom)

    Feltham, United Kingdom

    1 h-index

    21 publications

    231 citations

  2. Princeton University

    Princeton, United States

    1 h-index

    1 publications

    22 citations

  3. IRBM Science Park

    Pomezia, Italy

    1 h-index

    11 publications

    495 citations

  4. Dana-Farber Cancer Institute

    Boston, United States

    1 h-index

    1 publications

    15 citations

  5. Robert Gordon University

    Aberdeen, United Kingdom

    1 h-index

    1 publications

    13 citations

  6. Novartis Institutes for BioMedical Research

    Basel, Switzerland

    1 h-index

    5 publications

    75 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    1 h-index

    5 publications

    195 citations

  8. Gabrail Cancer Center

    Canton, United States

    1 h-index

    1 publications

    15 citations

1–8 of 39

Venues

  1. Bioorganic & Medicinal Chemistry Letters

    2 publications · 26 citations

    2

    h-index

  2. The Journal of Heart and Lung Transplantation

    1 publications · 15 citations

    1

    h-index

  3. American Heart Journal

    AHJ · 1 publications · 22 citations

    1

    h-index

  4. Alimentary Pharmacology & Therapeutics

    1 publications · 142 citations

    1

    h-index

  5. Disease-a-Month

    DM · 1 publications · 19 citations

    1

    h-index

1–5