Concepedia

Induced Hepatocyte Reprogramming

Induced Hepatocyte Reprogramming is a transdifferentiation method that directly converts somatic cells into functional hepatocyte-like cells through the ectopic expression of specific transcription factors or exposure to defined chemical cues, bypassing a pluripotent intermediate state.

12

Publications

420

Citations

114

Authors

47

Institutions

Publications per year

2017–2026

10

Parents

Publications

12

Small Molecules Facilitate Single Factor-Mediated Hepatic Reprogramming

Seung Chan Lee, Yimeng Gao, Kee-Pyo Kim et al. · Cell Reports · 2016 · 88 citations · Full text

, , +11

Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction

Daiki Nakamori, Hiroki Akamine, Kazuo Takayama et al. · Scientific Reports · 2017 · 70 citations · Full text

, , +13

In Vivo Cell Reprogramming towards Pluripotency by Virus-Free Overexpression of Defined Factors

Açelya Yılmazer, Irene de Lázaro, Cyrill Bussy et al. · PLoS ONE · 2013 · 45 citations · Full text

, , +13

The therapeutic potential of induced hepatocyte-like cells generated by direct reprogramming on hepatic fibrosis

Suhyun Park, Seon In Hwang, Jonghun Kim et al. · Stem Cell Research & Therapy · 2019 · 37 citations · Full text

, , +14

Direct chemical induction of hepatocyte‐like cells with capacity for liver repopulation

Yunfei Bai, Zhenghao Yang, Xiaochan Xu et al. · Hepatology · 2022 · 31 citations

, , +16

1–5 of 12

Authors

114

  1. DH
    Dong‐Wook Han

    Pusan National University, South Korea

    2 publications · 125 citations

    2

    h-index

  2. JK
    Jonghun Kim

    Konkuk University, South Korea

    2 publications · 125 citations

    2

    h-index

  3. SI
    Seon In Hwang

    Konkuk University, South Korea

    2 publications · 125 citations

    2

    h-index

  4. CD
    Cong Du

    Third Affiliated Hospital of Sun Yat-sen University, China

    1 publications · 12 citations

    1

    h-index

  5. CB
    Cyrill Bussy

    University of Manchester, United Kingdom

    1 publications · 45 citations

    1

    h-index

1–5 of 114

Institutions

47

  1. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

    Madrid, Spain

    2 h-index

    6 publications

    136 citations

  2. University of Chinese Academy of Sciences

    Beijing, China

    2 h-index

    5 publications

    107 citations

  3. Chinese Academy of Sciences

    Beijing, China

    2 h-index

    3 publications

    195 citations

  4. Center for Excellence in Molecular Cell Science

    Shanghai, China

    2 h-index

    3 publications

    207 citations

  5. Konkuk University

    Seoul, South Korea

    2 h-index

    16 publications

    1.1K citations

  6. Forest Institute

    Springfield, United States

    1 h-index

    7 publications

    147 citations

  7. Sungkyunkwan University

    Seoul, South Korea

    1 h-index

    9 publications

    333 citations

  8. The University of Osaka

    Osaka, Japan

    1 h-index

    1 publications

    70 citations

1–8 of 47

Venues

  1. Stem Cell Research & Therapy

    2 publications · 60 citations

    2

    h-index

  2. Scientific Reports

    1 publications · 70 citations

    1

    h-index

  3. The EMBO Journal

    1 publications · 22 citations

    1

    h-index

  4. Hepatology

    1 publications · 31 citations

    1

    h-index

  5. Nature Communications

    1 publications · 31 citations

    1

    h-index

1–5