Concepedia

Immune Synapse Engineering

Immune Synapse Engineering is a specialized methodology in immune cell engineering that involves the rational design and modulation of molecular interactions at the interface between immune cells and target cells to enhance or control immune activation, specificity, and signaling outcomes.

9

Publications

405

Citations

71

Authors

17

Institutions

Publications per year

2017–2026

7

Parents

Publications

9

Artificial antigen-presenting cells as a tool to exploit the immune `synapse'

Berent J. Prakken, Marca H. M. Wauben, Davide Genini et al. · Nature Medicine · 2000 · 131 citations

, , +12

A CS1-NKG2D Bispecific Antibody Collectively Activates Cytolytic Immune Cells against Multiple Myeloma

Wing Keung Chan, Siwen Kang, Youssef Youssef et al. · Cancer Immunology Research · 2018 · 110 citations · Full text

, , +17

Synapse-tuned CARs enhance immune cell anti-tumor activity

Peter Chockley, Jorge Ibañez-Vega, Giedre Krenciute et al. · Nature Biotechnology · 2023 · 57 citations · Full text

, , +10

Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR

Evangelia Kokalaki, Biao Ma, Mathieu Ferrari et al. · Molecular Therapy · 2023 · 33 citations · Full text

, , +17

Potentiating anti-tumor immunity by re-engaging immune synapse molecules

Xindi Zhou, Xu Tian, Changhe Li et al. · Cell Reports Medicine · 2025 · 19 citations · Full text

, , +17

1–5 of 9

Authors

71

  1. JI
    Jorge Ibañez-Vega

    St. Jude Children's Research Hospital, United States

    1 publications · 57 citations

    1

    h-index

  2. TR
    Tatiana Rizou

    The Francis Crick Institute, United Kingdom

    1 publications · 33 citations

    1

    h-index

  3. GV
    György Vereb

    University of Debrecen, Hungary

    1 publications · 18 citations

    1

    h-index

  4. WK
    Wing Keung Chan

    The Ohio State University, United States

    1 publications · 110 citations

    1

    h-index

  5. JB
    Joellen Barnett

    University of California San Diego, United States

    1 publications · 131 citations

    1

    h-index

1–5 of 71

Institutions

17

  1. Hungarian Academy of Sciences

    Budapest, Hungary

    1 h-index

    1 publications

    18 citations

  2. University of Debrecen

    Debrecen, Hungary

    1 h-index

    8 publications

    144 citations

  3. University College London

    London, United Kingdom

    1 h-index

    1 publications

    33 citations

  4. University of California San Diego

    San Diego, United States

    1 h-index

    7 publications

    917 citations

  5. CEINGE Biotecnologie Avanzate Franco Salvatore (Italy)

    Naples, Italy

    1 h-index

    2 publications

    34 citations

  6. University of Naples Federico II

    Naples, Italy

    1 h-index

    2 publications

    34 citations

  7. The Ohio State University

    Columbus, United States

    1 h-index

    12 publications

    1.3K citations

  8. Federico II University Hospital

    Naples, Italy

    1 h-index

    1 publications

    17 citations

1–8 of 17

Venues

  1. PLoS Computational Biology

    1 publications · 14 citations

    1

    h-index

  2. Molecular Therapy

    1 publications · 33 citations

    1

    h-index

  3. Nature Biotechnology

    1 publications · 57 citations

    1

    h-index

  4. Cancer Immunology Research

    1 publications · 110 citations

    1

    h-index

  5. Nature Medicine

    1 publications · 131 citations

    1

    h-index

1–5