Concepedia

Immune Synapse Disruption

Immune Synapse Disruption is a molecular mechanism employed by parasites to interfere with the formation or function of the immune synapse, thereby preventing effective T-cell activation and immune response coordination.

61

Publications

5.7K

Citations

522

Authors

221

Institutions

Publications per year

2017–2026

19

Parents

Publications

61

Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug

Alan G. Ramsay, Amy J. Johnson, Abigail M. Lee et al. · Journal of Clinical Investigation · 2008 · 594 citations · Full text

, , +17

Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells

Murat Tekgüç, James B. Wing, Motonao Osaki et al. · Proceedings of the National Academy of Sciences · 2021 · 450 citations · Full text

, , +17

Efficient HIV-1 transmission from macrophages to T cells across transient virological synapses

Fedde Groot, Sonja Welsch, Quentin J. Sattentau · Blood · 2008 · 242 citations · Full text

, , +16

Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy

Alan G. Ramsay, Andrew Clear, Gavin Kelly et al. · Blood · 2009 · 235 citations · Full text

, , +16

TGF-β–inducible microRNA-183 silences tumor-associated natural killer cells

Sarah S. Donatelli, Junmin Zhou, Danielle L. Gilvary et al. · Proceedings of the National Academy of Sciences · 2014 · 214 citations · Full text

, , +17

1–5 of 61

Authors

522

  1. PL
    Pamela L. Schwartzberg

    National Human Genome Research Institute, United States

    3 publications · 189 citations

    3

    h-index

  2. JG
    John G. Gribben

    Queen Mary University of London, United Kingdom

    2 publications · 829 citations

    2

    h-index

  3. MZ
    Maximilian Zeyda

    Medical University of Vienna, Austria

    2 publications · 120 citations

    2

    h-index

  4. JB
    James B. Wing

    The University of Osaka, Japan

    2 publications · 465 citations

    2

    h-index

  5. ML
    Michael L. Dustin

    New York University, United States

    2 publications · 79 citations

    2

    h-index

1–5 of 522

Institutions

221

  1. National Institutes of Health

    Bethesda, United States

    4 h-index

    12 publications

    861 citations

  2. University of Toronto

    Toronto, Canada

    4 h-index

    18 publications

    2.4K citations

  3. Kyoto University

    Kyoto, Japan

    3 h-index

    6 publications

    1K citations

  4. Ludwig-Maximilians-Universität München

    Munich, Germany

    3 h-index

    9 publications

    603 citations

  5. Inserm

    Paris, France

    3 h-index

    14 publications

    1.1K citations

  6. University College London

    London, United Kingdom

    3 h-index

    7 publications

    575 citations

  7. University of Cambridge

    Cambridge, United Kingdom

    3 h-index

    13 publications

    1.1K citations

  8. National Human Genome Research Institute

    Bethesda, United States

    3 h-index

    8 publications

    458 citations

1–8 of 221

Venues

  1. The Journal of Immunology

    JI · 8 publications · 435 citations

    8

    h-index

  2. Journal of Clinical Investigation

    JCI · 4 publications · 832 citations

    4

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 810 citations

    4

    h-index

  4. Blood

    4 publications · 626 citations

    4

    h-index

  5. Nature Communications

    3 publications · 144 citations

    3

    h-index

1–5