Concepedia

Immune Cell Persistence

Immune Cell Persistence is a biological construct that denotes the duration and functional maintenance of engineered immune cells within a host organism following therapeutic administration, distinguishing it from transient cellular activity by emphasizing sustained viability, proliferation, and immunological engagement in vivo.

66

Publications

7K

Citations

547

Authors

181

Institutions

Publications per year

2017–2026

27

Parents

Publications

66

Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition

Leonid Cherkassky, Aurore Morello, Jonathan Villena‐Vargas et al. · Journal of Clinical Investigation · 2016 · 1.1K citations · Full text

, , +17

Cord blood NK cells engineered to express IL-15 and a CD19-targeted CAR show long-term persistence and potent antitumor activity

E Liu, Yijiu Tong, Gianpietro Dotti et al. · Leukemia · 2017 · 811 citations

, , +16

Cutting Edge: Persistence of Transferred Lymphocyte Clonotypes Correlates with Cancer Regression in Patients Receiving Cell Transfer Therapy

Paul F. Robbins, Mark E. Dudley, John R. Wunderlich et al. · The Journal of Immunology · 2004 · 462 citations · Full text

, , +16

Designing and Maintaining the Mature TCR Repertoire

Christophe Viret, F. Susan Wong, Charles A. Janeway · Immunity · 1999 · 313 citations · Full text

, , +17

Optimization of IL13Rα2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma

Christine E. Brown, Brenda Aguilar, Renate Starr et al. · Molecular Therapy · 2017 · 298 citations · Full text

, , +17

1–5 of 66

Authors

547

  1. KP
    Karlis Pauksens

    Uppsala University Hospital, Sweden

    2 publications · 58 citations

    2

    h-index

  2. SV
    Stéphanie Volpe

    GlaxoSmithKline (Belgium), Belgium

    2 publications · 58 citations

    2

    h-index

  3. RJ
    Randolph J. Noelle

    Dartmouth College, United States

    2 publications · 292 citations

    2

    h-index

  4. TF
    Tino F. Schwarz

    GlaxoSmithKline (Belgium), Belgium

    2 publications · 58 citations

    2

    h-index

  5. MK
    Malcolm K. Brenner

    Baylor College of Medicine, United States

    2 publications · 285 citations

    2

    h-index

1–5 of 547

Institutions

181

  1. Heidelberg University

    Heidelberg, Germany

    4 h-index

    11 publications

    1.1K citations

  2. The University of Texas MD Anderson Cancer Center

    Houston, United States

    4 h-index

    24 publications

    15.7K citations

  3. National Cancer Institute

    Bethesda, United States

    3 h-index

    20 publications

    5.9K citations

  4. Inserm

    Paris, France

    3 h-index

    9 publications

    1.2K citations

  5. National Institutes of Health

    Bethesda, United States

    3 h-index

    15 publications

    5.1K citations

  6. Memorial Sloan Kettering Cancer Center

    New York, United States

    3 h-index

    7 publications

    5.6K citations

  7. Baylor College of Medicine

    Houston, United States

    3 h-index

    16 publications

    4.1K citations

  8. German Cancer Research Center

    Heidelberg, Germany

    3 h-index

    10 publications

    949 citations

1–8 of 181

Venues

  1. The Journal of Immunology

    JI · 7 publications · 796 citations

    7

    h-index

  2. Journal of Clinical Investigation

    JCI · 5 publications · 1.5K citations

    5

    h-index

  3. The Journal of Experimental Medicine

    3 publications · 563 citations

    4

    h-index

  4. European Journal of Immunology

    EJI · 3 publications · 172 citations

    3

    h-index

  5. Leukemia

    2 publications · 958 citations

    2

    h-index

1–5