Concepedia

Hypothesis-driven Association Testing

Hypothesis-Driven Association Testing is a candidate gene study approach that belongs to the class of genetic association testing methods and is distinguished by its explicit focus on evaluating specific pre-specified biological hypotheses about the relationship between a targeted gene or genetic variant and a trait of interest.

18

Publications

1.2K

Citations

94

Authors

47

Institutions

Publications per year

2017–2026

4

Variants

Candidate Gene Association Testing

Parents

Publications

18

Testing association patterns: issues arising and extensions

Hal Whitehead, Lars Bejder, C. Andrea Ottensmeyer · Animal Behaviour · 2005 · 171 citations

, , +8

Power and Design Considerations for a General Class of Family-Based Association Tests: Quantitative Traits

Christoph Lange, Dawn L. DeMeo, Nan M. Laird · The American Journal of Human Genetics · 2002 · 145 citations · Full text

, , +14

Voxelwise gene-wide association study (vGeneWAS): Multivariate gene-based association testing in 731 elderly subjects

Derrek P. Hibar, Jason L. Stein, Omid Kohannim et al. · NeuroImage · 2011 · 137 citations

, , +11

Hypothesis-driven candidate genes for schizophrenia compared to genome-wide association results

Amanda Collins, Young-Jae Kim, Pamela Sklar et al. · Psychological Medicine · 2011 · 99 citations

, , +17

HYST: A Hybrid Set-Based Test for Genome-wide Association Studies, with Application to Protein-Protein Interaction-Based Association Analysis

Miaoxin Li, Johnny S. H. Kwan, Pak C. Sham · The American Journal of Human Genetics · 2012 · 93 citations · Full text

, , +12

1–5 of 18

Authors

94

  1. XL
    Xihong Lin

    Harvard University, United States

    2 publications · 161 citations

    2

    h-index

  2. PF
    Patrick F. Sullivan

    University of North Carolina at Chapel Hill, United States

    2 publications · 153 citations

    2

    h-index

  3. HG
    Herbert Gerjuoy

    Educational Testing Service, United States

    1 publications · 15 citations

    1

    h-index

  4. HZ
    Hongyu Zhao

    Yale University, United States

    1 publications · 25 citations

    1

    h-index

  5. NJ
    Neda Jahanshad

    University of Southern California, United States

    1 publications · 137 citations

    1

    h-index

1–5 of 94

Institutions

47

  1. Harvard University

    Cambridge, United States

    3 h-index

    7 publications

    684 citations

  2. University of Toronto

    Toronto, Canada

    2 h-index

    4 publications

    204 citations

  3. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    2 h-index

    4 publications

    351 citations

  4. New York Genome Center

    New York, United States

    2 h-index

    2 publications

    143 citations

  5. Columbia University

    New York, United States

    2 h-index

    3 publications

    208 citations

  6. Translational Genomics Research Institute

    Phoenix, United States

    1 h-index

    1 publications

    137 citations

  7. Ostfalia University of Applied Sciences

    Wolfenbüttel, Germany

    1 h-index

    2 publications

    38 citations

  8. University of Maryland, Baltimore

    Baltimore, United States

    1 h-index

    7 publications

    245 citations

1–8 of 47

Venues

  1. The American Journal of Human Genetics

    AJHG · 5 publications · 338 citations

    5

    h-index

  2. NeuroImage

    1 publications · 137 citations

    1

    h-index

  3. HAL (Le Centre pour la Communication Scientifique Directe)

    Repository · 1 publications · 14 citations

    1

    h-index

  4. Information Sciences

    1 publications · 19 citations

    1

    h-index

  5. Neuropsychopharmacology

    1 publications · 30 citations

    1

    h-index

1–5