Concepedia

Human Intestinal Fluid

Human Intestinal Fluid is a physiologically representative biological medium collected from the small intestine of human subjects, distinguished by its specific composition of bile salts, phospholipids, cholesterol, enzymes, and electrolytes that collectively simulate the biochemical and biophysical environment relevant for in vitro dissolution testing of oral drug products.

517

Publications

31.1K

Citations

2K

Authors

639

Institutions

Publications per year

2017–2026

82

Variants

Hif

Parents

Publications

517

Short chain fatty acids in human large intestine, portal, hepatic and venous blood.

John H. Cummings, E W Pomare, W J Branch et al. · Gut · 1987 · 3.1K citations · Full text

, , +16

Dissolution Media Simulating Conditions in the Proximal Human Gastrointestinal Tract: An Update

Ekarat Jantratid, Niels Janssen, Christos Reppas et al. · Pharmaceutical Research · 2008 · 745 citations

, , +14

Characterization of the Human Upper Gastrointestinal Contents Under Conditions Simulating Bioavailability/Bioequivalence Studies

Lida Kalantzi, Konstantinos Goumas, V. Kalioras et al. · Pharmaceutical Research · 2005 · 653 citations

, , +14

Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin–induced intestinal fluid secretion

Tonghui Ma, Jay R. Thiagarajah, Hong Yang et al. · Journal of Clinical Investigation · 2002 · 632 citations · Full text

, , +10

Intestinal fluid volumes and transit of dosage forms as assessed by magnetic resonance imaging

Carsten Schiller, Carolin Fröhlich, Werner Siegmund et al. · Alimentary Pharmacology & Therapeutics · 2005 · 597 citations

, , +17

1–5 of 517

Authors

2K

  1. PA
    Patrick Augustijns

    KU Leuven, Belgium

    32 publications · 2K citations

    25

    h-index

  2. JT
    Jan Tack

    KU Leuven, Belgium

    20 publications · 1.6K citations

    20

    h-index

  3. JB
    Joachim Brouwers

    KU Leuven, Belgium

    23 publications · 1.4K citations

    19

    h-index

  4. CR
    Christos Reppas

    National and Kapodistrian University of Athens, Greece

    15 publications · 2.4K citations

    14

    h-index

  5. MV
    Maria Vertzoni

    National and Kapodistrian University of Athens, Greece

    11 publications · 652 citations

    10

    h-index

1–5 of 2K

Institutions

639

  1. KU Leuven

    Leuven, Belgium

    26 h-index

    127 publications

    8.7K citations

  2. National and Kapodistrian University of Athens

    Athens, Greece

    15 h-index

    42 publications

    4.8K citations

  3. Uppsala University

    Uppsala, Sweden

    13 h-index

    30 publications

    2.6K citations

  4. University of Strathclyde

    Glasgow, United Kingdom

    12 h-index

    46 publications

    1.2K citations

  5. University of California, San Francisco

    San Francisco, United States

    10 h-index

    31 publications

    7.1K citations

  6. University of Copenhagen

    Copenhagen, Denmark

    9 h-index

    24 publications

    808 citations

  7. AstraZeneca (Sweden)

    Södertälje, Sweden

    9 h-index

    22 publications

    3.5K citations

  8. Goethe University Frankfurt

    Frankfurt am Main, Germany

    8 h-index

    12 publications

    3.7K citations

1–8 of 639

Venues

  1. Gut

    31 publications · 4.4K citations

    22

    h-index

  2. Pharmaceutical Research

    21 publications · 3.3K citations

    19

    h-index

  3. Molecular Pharmaceutics

    17 publications · 1.6K citations

    17

    h-index

  4. European Journal of Pharmaceutical Sciences

    17 publications · 963 citations

    17

    h-index

  5. Gastroenterology

    18 publications · 805 citations

    16

    h-index

1–5