Concepedia

Hotspot Activation

Hotspot Activation is a methodological framework in genetics that identifies and characterizes genomic regions with elevated recombination rates by integrating epigenomic markers and sequence motifs to distinguish functional recombination initiation sites from background recombination activity.

44

Publications

2.4K

Citations

145

Authors

69

Institutions

Publications per year

2017–2026

10

Parents

Publications

44

Opioid Limbic Circuit for Reward: Interaction between Hedonic Hotspots of Nucleus Accumbens and Ventral Pallidum

Kyle S. Smith, Kent Berridge · Journal of Neuroscience · 2007 · 456 citations · Full text

, , +17

Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the <i>M</i> 26 meiotic recombination hotspot in <i>Schizosaccharomyces pombe</i>

Ning Kon, Michelle D. Krawchuk, B. Greg Warren et al. · Proceedings of the National Academy of Sciences · 1997 · 153 citations · Full text

, , +15

Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populations

Ingrid Berg, Rita Neumann, Shriparna Sarbajna et al. · Proceedings of the National Academy of Sciences · 2011 · 140 citations · Full text

, , +15

A heteromeric protein that binds to a meiotic homologous recombination hot spot: correlation of binding and hot spot activity.

Wayne P. Wahls, Gerald R. Smith · Genes & Development · 1994 · 112 citations · Full text

, , +17

Structure-dependent Recombination Hot Spot Activity of GAA·TTC Sequences from Intron 1 of the Friedreich's Ataxia Gene

Ruhee Dere, Alexandre A. Vetcher, Robert D. Wells · Journal of Biological Chemistry · 2004 · 90 citations · Full text

, , +14

1–5 of 44

Authors

145

  1. GR
    Gerald R. Smith

    Fred Hutch Cancer Center, United States

    7 publications · 507 citations

    7

    h-index

  2. WP
    Wayne P. Wahls

    University of Arkansas for Medical Sciences, United States

    7 publications · 384 citations

    7

    h-index

  3. WW
    Walter W. Steiner

    Niagara University, United States

    4 publications · 111 citations

    4

    h-index

  4. MK
    Mari K. Davidson

    University of Arkansas for Medical Sciences, United States

    3 publications · 60 citations

    3

    h-index

  5. PM
    Petko M. Petkov

    Jackson Laboratory, United States

    3 publications · 158 citations

    3

    h-index

1–5 of 145

Institutions

69

  1. Fred Hutch Cancer Center

    Seattle, United States

    7 h-index

    18 publications

    1.5K citations

  2. University of Arkansas for Medical Sciences

    Little Rock, United States

    4 h-index

    12 publications

    318 citations

  3. Niagara University

    Lewiston, United States

    3 h-index

    4 publications

    94 citations

  4. Jackson Laboratory

    Bar Harbor, United States

    3 h-index

    13 publications

    750 citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    3 h-index

    7 publications

    398 citations

  6. Bangor University

    Bangor, United Kingdom

    2 h-index

    7 publications

    184 citations

  7. Vanderbilt University

    Nashville, United States

    2 h-index

    6 publications

    775 citations

  8. Helsinki University Hospital

    Helsinki, Finland

    1 h-index

    5 publications

    200 citations

1–8 of 69

Venues

  1. Genetics

    11 publications · 404 citations

    11

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 388 citations

    4

    h-index

  3. Journal of Molecular Biology

    JMB · 2 publications · 129 citations

    2

    h-index

  4. PLoS ONE

    2 publications · 28 citations

    2

    h-index

  5. Geophysical Research Letters

    2 publications · 37 citations

    2

    h-index

1–5