Concepedia

Host-pathogen Genetic Interactions

Host-Pathogen Genetic Interactions is a theoretical construct in immunogenetics that characterizes the dynamic interplay between host and pathogen genomes, where genetic variation in the host influences susceptibility to infection and pathogen evolution, and reciprocally, pathogen genetic determinants affect host immune recognition and response outcomes.

283

Publications

18.8K

Citations

1.8K

Authors

735

Institutions

Publications per year

2017–2026

90

Parents

Publications

283

A Mutation in the Interferon-γ –Receptor Gene and Susceptibility to Mycobacterial Infection

Melanie J. Newport, Clare Huxley, Sara Huston et al. · New England Journal of Medicine · 1996 · 1.2K citations

, , +17

The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoV-2 virus pandemic

European Journal of Human Genetics · 2020 · 889 citations · Full text

, , +17

Immune determinants of COVID-19 disease presentation and severity

Petter Brodin · Nature Medicine · 2021 · 698 citations

, , +14

MHC heterozygosity confers a selective advantage against multiple-strain infections

Dustin J. Penn, Kristy Damjanovich, Wayne K. Potts · Proceedings of the National Academy of Sciences · 2002 · 690 citations · Full text

, , +17

Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

David M. Tobin, Francisco J. Roca, Sungwhan F. Oh et al. · Cell · 2012 · 572 citations · Full text

, , +16

1–5 of 283

Authors

1.8K

  1. FP
    Fernando Pardo‐Manuel de Villena

    University of North Carolina at Chapel Hill, United States

    5 publications · 508 citations

    6

    h-index

  2. DM
    Danielle Malo

    McGill University, Canada

    5 publications · 193 citations

    5

    h-index

  3. ES
    Erwin Schurr

    McGill University, Canada

    5 publications · 237 citations

    5

    h-index

  4. JH
    John H. Weis

    University of Utah, United States

    4 publications · 408 citations

    4

    h-index

  5. MT
    Martin T. Ferris

    University of North Carolina at Chapel Hill, United States

    4 publications · 491 citations

    4

    h-index

1–5 of 1.8K

Institutions

735

  1. Centre National de la Recherche Scientifique

    Paris, France

    13 h-index

    40 publications

    1.8K citations

  2. Inserm

    Paris, France

    11 h-index

    29 publications

    1.3K citations

  3. National Institutes of Health

    Bethesda, United States

    11 h-index

    38 publications

    5.4K citations

  4. McGill University

    Montreal, Canada

    10 h-index

    44 publications

    1.7K citations

  5. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    10 h-index

    34 publications

    4K citations

  6. Institut Pasteur

    Paris, France

    9 h-index

    22 publications

    1.3K citations

  7. University of Edinburgh

    Edinburgh, United Kingdom

    9 h-index

    34 publications

    1.8K citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    8 h-index

    49 publications

    4.5K citations

1–8 of 735

Venues

  1. Infection and Immunity

    IAI · 24 publications · 1.2K citations

    17

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 1.5K citations

    11

    h-index

  3. PubMed

    Repository · 11 publications · 317 citations

    10

    h-index

  4. PLoS ONE

    9 publications · 237 citations

    9

    h-index

  5. The Journal of Immunology

    JI · 7 publications · 381 citations

    7

    h-index

1–5